Koninklijke Philips Corporation N.v.

Philips Gmbh

Jarich Willem Spliethoff

Bernardus Hendrikus Wilhelmus Hendriks

Christian Reich

Gerhardus Wilhelmus Lucassen

Martinus Bernardus Van Der Mark

Robert Johannes Frederik Homan

Waltherus Cornelis Jozef Bierhoff

Drazenko Babic

Anja Van De Stolpe

Vishnu Vardhan Pully

Axel Winkel

Stephan Voss

Susanne Dorien Van Den Berg-Dams

Aleksandra Popovic

Grzegorz Andrzej Toporek

Jeroen Jan Lambertus Horikx

Ronaldus Frederik Johannes Holthuizen

Marjolein Van Der Voort

Nijs Cornelis Van Der Vaart

Torre Michelle Bydlon

Manfred Mueller

Rami Nachabe

Klaas Cornelis Jan Wijbrans

Peter George Van De Haar

Johan Juliana Dries

Theodoor Jacques Marie Ruers

Edward Vuurberg

Johanneke Gerrigje Groen

Marjolen Van Der Voort

Joanneke Gerrigje Groen

Jan Rongen

Keshav Simhadri

The present invention relates to guidance during a medical intervention. In order to provide an improved navigation support with a facilitated setup, a system () for navigation support is provided. An image data input () receives a plurality of acquired 2D X-ray images of a subject's body from different angles. A set of markers, which are visible in X-ray images and which are detectable by a navigation system, is assigned to the subject. A marker detecting arrangement () is provided that detects a current spatial location of the markers assigned to the subject. A data processor () reconstructs a 3D volume of the subject based on the plurality of 2D X-ray images. At least a part of the markers is arranged outside the volume covered by the reconstructed 3D volume of the subject, while the markers are visible in the 2D X-ray images. The data processor () identifies the markers in the 2D X-ray images based on image data of the plurality of 2D X-ray images outside the 3D volume and determines a spatial location of the markers in relation to the 3D volume of the subject. The data processor () also registers the reconstructed 3D volume of the subject to a current spatial position of the subject based on the detected current spatial location of the markers and the determined spatial location of the markers in relation to the 3D volume of the subject. An output interface () provides the registered reconstructed 3D volume for navigation.

Navigation support

An orthopedic pin () for optically analyzing a bone region () includes an elongate shaft () and at least one optical fiber (). The elongate shaft has a circular outer cross section with a first diameter (D), a distal end () for insertion into bone, a proximal end (), and an optical connector portion () disposed towards the proximal end (). The at least one optical fiber () extends within the elongate shaft () between the optical connector portion (), and the distal end () for transmitting optical radiation between the optical connector portion () and the bone region () when the distal end () is inserted into the bone region (). The optical connector portion () comprises a reduced-diameter portion (). The reduced-diameter portion () extends along at least a portion of the elongate shaft (), and has an outer cross section comprising a width (Drd) perpendicularly with respect to the elongate shaft (). The width (Drd) is less than the first diameter (D).

Orthopedic pin for optically analyzing a bone region

A system SY for determining a tissue type TY of a tissue region TR is provided in which the distal ends OFDEof at least three optical fibers define a plurality of intersecting optical paths IOPwithin the tissue region TR. A tissue signal Qindicative of a tissue type TY for the respective optical path IOPis generated from said spectral measurement data SMD corresponding to each of the plurality of intersecting optical paths IOP. Each tissue signal Qis compared with a reference threshold QRT for the tissue type, and with an average of the tissue signals QMA. At least a portion of the tissue region is identified as the tissue type TY if i) every tissue signal Qin the tissue region TR indicates that its corresponding tissue is not the tissue type TY in the comparison with the reference threshold QRT and ii) at least one of the tissue signals Qin the tissue region TR lies between the average QMA of the tissue signals Qand the reference threshold QRT, and a difference Δ between the at least one tissue signal Qand the average QMA of the tissue signals Qexceeds a predetermined value ΔP.

Tumor margin assessment

A system may generally comprise a tracking device, an ultrasound device and a processing unit. A position and orientation of the ultrasound device may be traceable by the tracking device. The processing unit may be configured (i) to receive 3D information of a region of interest in relation to a marker, with both the region of interest and the marker being located within a body, (ii) to determine the position of the marker relative to the ultrasound device based on an ultrasound image of the body including the marker, and (iii) to determine the position and orientation of the ultrasound device relative to the tracking device. The system may further comprise a visualization device and the processing unit may further be configured to generate a visualization of the region of interest in relation to an outer surface of the body.

Systems providing images guiding surgery

A biopsy device is provided comprising a tubular member, a hollow shaft and an elongated fiber body. The hollow shaft may have a distal end and a shaft, wherein a laterally (sidewardly) facing notch is formed in the distal portion of the shaft. The elongated fiber body may include at least one optical fiber, preferably at least two optical fibers, with a distal end. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The fiber body is movable within the shaft, between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.

System with photonic biopsy device for obtaining pathological information

A biopsy device includes a tubular member, a hollow shaft and an elongated fiber body having at least one optical fiber. The hollow shaft has a laterally (sidewardly) facing notch in its distal portion. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The shaft is movable between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.

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Utrecht, Netherlands

Jarich Willem Spliethoff