Kaleido Biosciences, Inc.

Cubist Pharmaceuticals, Incorporated

Dsm Nutritional Products Inc.

Jared Silverman

Geoffrey Von Maltzahn

John M Geremia

John Miles Milwid

Yvonne J Yamanaka

Jason J Hill

Dennis D Keith

John F Finn

Michael Morytko

Tsvetelina Ivanova Lazarova

Alan D Watson

Dale Christensen

Yan Zhang

Ian Parr

Jim Siedlecki

Jacob Rosenblum Rubens

Xian Yang Yu

Xiang Yang Yu

Jeffrey Alder

Lawrence Mortin

Jack Milwid

Andrew Van Praagh

Geoffrey A Von Maltzahn

Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said gycan therapeutics, e.g. in cancer therapy.

Glycan therapeutic compositions and related methods thereof

Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said glycan therapeutics, e.g. in cancer therapy.

Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

Glycan therapeutics and method of treating conditions associated with TMAO

Glycan therapeutics and related methods thereof

Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

Glycan therapeutics for reducing blood ammonia

Daptomycin can be used for biofilm treatment (particularly central venous catheter salvage forinfected catheters). Catheter salvage with daptomycin shows rapid cidality, activity against stationary phase bacteria, and penetration and activity in biofilms. The present inventions provide formulations, methods, and articles of manufacture useful for biofilm treatment or catheter salvage involving daptomycin. Particular formulations include daptomycin in lactated Ringer's solution having a rapid kill curve against the bacteria of the biofilm.

Daptomycin for the treatment of biofilm and catheter salvage

The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.

Lipopeptides as antibacterial agents

Growing community of inventors

Brookline, MA, United States of America

Jared Silverman