Mount Sinai Hospital Corporation

Janet Rossant

Daniel J Dumont

Terry P Yamaguchi

Satoshi Tanaka

Martin L Breitman

Martin L Breitman, Deceased

Tilo Kunath

Jo-Ann Breitman

Stable pluripotent trophoblast stem (TS) cell lines and uses of the cell lines are described. The cell lines comprise cells that (i) are capable of indefinite proliferation in vitro in an undifferentiated state, and (ii) are capable of differentiation into cells of the trophoblast lineage in vivo.

Trophoblast cell preparations

Novel receptor tyrosine kinase protein and isoforms thereof which are expressed in cells of the endothelial lineage, and DNA segments encoding the novel protein and isoforms thereof are disclosed. Methods for identifying ligands which are capable of binding to the receptor protein and methods for screening for agonist or antagonist substances of the interaction of the protein and a ligand are also disclosed.

Receptor tyrosine kinase

Nucleic acid encoding tek receptor tyrosine kinase

Growing community of inventors

Toronto, Canada

Janet Rossant