Other

Jane Spetzler

Neil I Goldstein

Arthur J Blume

Per Hertz Hansen

Renee Brissette

Renuka Pillutla

Søren Østergaard

Lauge Schäffer

Jakob Brandt

Peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors with either agonist or antagonist activity and identified from various peptide libraries are disclosed. This invention also identifies at least two different binding sites, which are present on insulin and insulin-like growth factor receptors, and which selectively bind the peptides of this invention. As agonists, certain of the peptides of this invention may be useful for development as therapeutics to supplement or replace endogenous peptide hormones. The antagonists may also be developed as therapeutics.

Insulin and IGF-1 receptor agonists and antagonists

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Copenhagen, Denmark

Jane Spetzler