Alza Corporation

Jane E Shaw

Robert M Gale

John Urquhart

Alfred A Amkraut

Santosh K Chandrasekaran

Peter W Ramwell

Hideo Shio

Kumar Chandrasekaran

A method of preventing sensitization in transdermal drug delivery by the inclusion of a corticosteroid, which will be coextensively coadministered with the sensitizing agent.

Prevention of contact allergy by coadministration of a corticosteroid

A method of preventing sensitization in transdermal drug delivery by the inclusion of a corticosteroid, which will be co-extensively coadministered with the sensitizing agent.

A method of preventing sensitization in transdermal drug delivery by the inclusion of a corticosteroid, which wll be co-extensively coadministered with the sensitizing agent.

A method is disclosed for treating an ischemic condition. The method comprises coadministering topically and internally a vasodilator to a patient having the condition for treating the condition.

Method for treating ischemic conditions

A method is disclosed for treating an ischemic condition. The method comprises coadministering topically and internally a vasodilator to a patient having the condition for treating said condition.

Method comprising transdermal and buccal treatment of angina

Method for treating ischemic conditions by administering drug by two

Method and therapeutic system in the form of a bandage that administer scopolamine base transdermally in an initial pulse of 10 to 200 .mu.g/cm.sup.2 of skin that quickly brings the concentration of scopolamine in the plasma to a level at which emesis and nausea are inhibited without intolerable side effects, followed by a substantially constant dosage in the range of 0.3 to 15 .mu.g/hr that holds said level. The bandage is a four-layer laminate of, from the top: a protective backing; a gelled, mineral oil-polyisobutene-scopolamine reservoir lamina that is the source of the constant dosage; a microporous membrane that controls the constant dosage rate; and a gelled, mineral oil-polyisobutene-scopolamine adhesive layer that is the source of the pulse dose and the means by which the bandage is attached to the skin.

Method for administering scopolamine transdermally

Method and therapeutic system for administering scopolamine transdermally

Method and therapeutic system in the form of a bandage for providing chemotherapy transdermally by administering certain drugs to unbroken skin in an initial priming dose that quickly brings the systemic concentration of drug to a therapeutic level, followed by a substantially constant dosage that holds said level. The bandage is a four-layer laminate of, from the top: a protective backing; a drug reservoir lamina that is the source of the constant dosage; a microporous membrane that controls the constant dosage rate; and an adhesive layer that is the source of the priming dose and the means by which the bandage is attached to the skin.

Method and therapeutic system for providing chemotherapy transdermally

Bandage for transdermally administering scopolamine to prevent nausea

Polymeric materials having at least one exposed surface rendered as a release means for platelet aggregation inhibiting agent by serving as a reservoir for release of aggregation inhibiting prostaglandin. The polymeric surface can also be both platelet aggregation agent releasing and non-thrombogenic agent releasing by having together on the polymeric surface an aggregation inhibiting prostaglandin and an anti-coagulant which are easily released from the surface when in close contact with the blood, plasma or platelets.

Growing community of inventors

Atherton, CA, United States of America

Jane E Shaw