Ontario Institute for Cancer Research (Oicr)

Ontario Institute for Cancer Research

Jane Bayani

Paul Boutros

Vasundara Venkateswaran

John Bartlett

Jacques Lapointe

John M S Bartlett

Cindy Q Yao

Linh Nguyen

Paul C Boutros

David Berman

Palax Patel

Paul Park

Robert Lesurf

Anna Ying-wah Lee

Simone Chevalier

Ralph Buttyan

Nadia Boufaied

There is described herein a method of prognosing endocrine-only treatment in a subject with breast cancer, the method comprising: a) providing a tumor sample of the breast cancer; b) determining the expression level of at least 40 of the genes listed in Table 4 in the tumor sample; c) comparing said expression levels to a reference expression level of the group of genes from control samples from a cohort of subjects; and d) determining the residual risk associated with the breast cancer; wherein a statistically significant difference or similarity in the expression of the group of genes compared to the reference expression level corresponds to a residual risk associated with breast cancer.

Gene signature of residual risk following endocrine treatment in early breast cancer

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Richmond Hill, Canada

Jane Bayani