Abbott Laboratories Corporation

Basf Aktiengesellschaft

J&uuml;rgen Zeidler

J&ouml;rg Breitenbach

J&ouml;rg Rosenberg

J&ouml;rg Neumann

Joerg Rosenberg

Gunther Berndl

Ulrich Reinhold

Werner Maier

Andreas Kleinke

Bernd Leipold

Christiane Vollgraf

A solid or semisolid, at least two-phase active ingredient-containing formulation in which there is multiparticulate incorporation of one of the two phases into a matrix of the other phase, and at least one of the phases contains at least one active ingredient, obtainable by introducing particles of one phase into the other phase in a plastic state, and shaping the material while still plastic.

Multiphase active ingredient-containing formulations

Solvent-free noncrystalline bioactive substances are prepared from the corresponding crystalline bioactive substances in an extruder by melting the substances in the extruder under reduced pressure and in the absence of auxiliaries, cooling and comminuting.

Method for producing solvent-free noncrystalline biologically active substances

Solid, elongate dosage forms ( ) with a long axis ( ) and with a length (L) which is defined by projection of the ends ( ) of the dosage form to the long axis, where a cross-sectional area ( ) oriented perpendicular to the long axis ( ) has an area which is variable along the long axis ( ) and increases from a cross-sectional area ( ) which is located between the ends ( ) and has a minimal area essentially continuously toward the two ends ( ) up to in each case a cross-sectional area ( and respectively) with a maximal area, wherein the distance of the maximal cross-sectional area ( ) which is located near one end ( ) from the maximal cross-sectional area ( ) which is located near the other end ( ) is, projected on the long axis ( ), more than half the length (L) of the dosage form ( ), are described.

Cleavable solid dosage forms and method for the production thereof

A fast-acting analgesic comprises as analgesic substance ibuprofen in an adjuvant matrix with a porous structure and a density of greater than 1 and up to 2.5 g/cm,.

Fast-acting analgesic

Solid medicaments obtained by extrusion of an isomalt-containing polymer-active substance melt

Growing community of inventors

Mutterstadt, Germany

Jürgen Zeidler

Growing community of inventors

Mutterstadt, Germany

J&uuml;rgen Zeidler

Jürgen Zeidler