Medimmune Limited

Janardhanan Anand Subramony

Roger Wongjung Liu

Corbin Zean Clawson

Michael C Song

Sergei Pechenov

Puneet Tyagi

A methodology to track patient usage of an autoinjector (AI) device, and to an external or electronic adaptor (eAdaptor) adapted to be used with the AI are disclosed. The eAdaptor contains sensors (including but not limited to a temperature sensor, a sound sensor, a vibration sensor and a magnetic sensor system), a display, a microprocessor, a real time clock, and communication systems that enables the eAdaptor to capture and confirm autoinjector (AI) use, as well as injection information, and transmit such information wirelessly to a smart phone or any other data receiving system or device. Also disclosed are an internal logic to operate the eAdaptor and a smart device APP that pairs with the internal logic to guide the patients with graphical user interface (GUI) displays on the smart device.

Device accessory for digitally monitoring autoinjector usage for improved compliance, remote patient monitoring, and adherence

The present invention provides formulations for oral administration of GLP-1 peptide analogs, methods of making such formulations, and methods of treatment using such formulations.

Oral delivery of GLP-1 peptide analogs

A smart plunger rod adapted to push a medication out of a syringe is disclosed. The plunger rod comprises a shaft sized and dimensioned to act on a piston on the syringe and a finger actuated head portion containing at least two subunits of a wireless sensor. In a pre-activation configuration, the subunits are spaced apart from each other by a physical barrier and the wireless sensor is non-operational. In a post-activation configuration, the subunits are connected to each other and the sensor is operational to send a signal. A user activates the finger actuated head portion to reversibly move the physical barrier and moves the plunger rod from the pre-activation configuration to the post-activation configuration. The signal sent by the sensor comprises information relating to ejecting the medication out of the syringe, and is received by a remote receiver.

Embedded multiple-part sensor within a plunger rod to capture and transit injection information

Drug delivery implement

Drug delivery implement with translucent housing

Growing community of inventors

Gaithersburg, MD, United States of America

Janardhanan Anand Subramony