Council of Scientific and Industrial Research

Janardan Singh

Sushil Kumar

Suman Preet Singh Khanuja

Madan Mohan Gupta

Anil Kumar Singh

Dharmendra Saikia

Anil Kumar Gupta

Ram Kishor Verma

Santosh Kumar Srivastava

Anirban Pal

Chandeshwar Nath

Rattan Lal Bindra

Subhash Chandra Singh

Vinay Kumar Khanna

Ashok Kumar Agrawal

Dnyaneshwar Umrao Bawankule

Anupam Maurya

Shikha Gupta

The present invention relates to bioactive extracts its fractions and isolation of compound from. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D, Cholinergic (muscarinic) and Serotonergic (5HT) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-demethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and &#x3b1;-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkaloids of formula 1 and 2 from the leaves of. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions ofand in the isolated compounds &#x3b1;-yohimbine, reserpiline and in a mixture 10-demethoxyreserpiline and 11-demethoxyreserpiline in 1:1.5 ratios for treating psychosis without any extra pyramidal symptoms (EPS). 

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An herbal dietary supplement composition for lactating mothers, comprising the required quantum of one or more herbs selected from Groups A to D, wherein the herbs from Group A being comprised of medicinal plant materials having galactagogue properties, Group B being comprised of medicinal plant materials having adaptogenic and anti-stress properties, Group C being comprised medicinal plant materials having hepatoprotective properties and Group D being comprised of medicinal plant materials having digestive and appetite improving properties, along with a required quantum of additives selected from nutritive flour and optional frying, flavoring, coloring and dressing agents, and a process for preparing the composition.

Composition of herbal biscuits for lactating mothers acting as dietary supplement and process for preparation thereof

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Lucknow, India

Janardan Singh