University of Zürich

Biogen International Neuroscience Gmbh

Janaky Coomaraswamy

Jan Grimm

Roger Nitsch

Christoph Hock

Paul H Weinreb

Fabio Montrasio

Maria Grazia Barenco Montrasio

Jean-Luc Baeriswyl

Omar Quintero-Monzon

Paul Weinreb

Provided are TAR DNA-binding protein of 43 kDa (TDP-43)-specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, kits, and solid supports related to TDP-43-specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively.

TDP-43 specific binding molecules

Provided are novel TAR DNA-binding proteins of 43 kDa ('TDP-43')-specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, kits, and solid supports related to TDP-43-specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively.

Growing community of inventors

Zurich, Switzerland

Janaky Coomaraswamy