Academisch Ziekenhuis Leiden (h.o.d.n. Lumc)

Ludwig Institute for Cancer Research Limited

Stichting Voor De Technische Wetenschappen

Academisch Ziekenhuis Leiden

Cornell Research Foundation Inc.

Memorial Sloan Kettering Cancer Center

Universiteit Leiden

Leiden University Medical Center

Inova Diagnostics, Inc.

Other

Academisch Medisch Centrum

Modiquest B.v.

Chiralix B.v.

Octoplus Technologies B.v.

Academisch Ziekenhuis Leiden (h.o.d.n. Leids Universitair Medisch Centrum)

Jan Wouter Drijfhout

Lloyd J Old

Yao-tseng Chen

Matthew J Scanlan

Gerardus Jozef Maria Pruijn

Gerd J Ritter

Ali O Gure

Alexander Knuth

Waltherus Jacobus Wilhelmus Van Venrooij

Martinus Adrianus Maria Van Boekel

Elke Jäger

Petrus Hendricus Nibbering

Robert Alexander Cordfunke

Jan Kessler

Marieke Griffioen

Waltherus Jacobus Van Venrooij

Martinus Adrianus Van Boekel

Gerardus Jozef Pruijn

Cornelis Johannes Maria Melief

Elke J&auml;ger

Gilles Philippus Van Wezel

Leendert Adrianus Trouw

Michael Mahler

René Toes

Michael Keith Richardson

Peter Van Veelen

Harald Martijn Ijsbrand Kerkkamp

Michella Manon Voet

Pieter Hiemstra

Johannes Jakobus Grote

Tom Huizinga

Michael Pfreundschuh

Ugur Sahin

Ozlem Tureci

Jozef Maria Hendrik Raats

Floris Petrus Johannes Theodorus Rutjes

Knuth Alexander

Richard Hendrik Blaauw

Cornelis Joseph Maria Melief

Ferdinand Antonius Ossendorp

Cornelis Johannes Melief

Maartje Johanna Nell

Guido Vincent Bloemberg

Sebastianus Antonius Johannes Zaat

Ali Gur&eacute;

Frits Koning

Elisabeth Hermine Adriane Spaenij-Dekking

Anna De Breij

Marcel Jan Vonk

Ludvig Magne Sollid

Stephan Neil Mcadam

The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.

Bioactive peptides derived from snakes

The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.

Compositions and methods for the diagnosis of rheumatoid arthritis

The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.

PRAME derived peptides and immunogenic compositions comprising these

The invention relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for in the treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.

Antimicrobial peptide and uses thereof

Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.

Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and assay kit

Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit

The disclosure relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.

Antimicrobial peptide

The present invention relates to conjugates comprising a peptide of at least 10 amino acid residues comprising the amino acid sequence GITELKKL (residues 383-390 of SEQ ID NO: 3) for induction of potent humoral and cellular immune responses when administered to subjects having antibodies against tetanus toxoid. In one embodiment the invention relates to a prophylactic and therapeutic vaccine and in a further embodiment the invention relates to the treatment or prevention of cancer or an infectious disease.

Peptides, conjugates and method for increasing immunogenicity of a vaccine

Prame derived peptides and immunogenic compositions comprising these

The invention relates to peptides which bind to MHC Class I and to MHC Class II molecules. These peptides are useful in different therapeutic and diagnostic contexts.

Method for inducing cell lysis with immunogenic portions of NY-ESO-1 protein

A liposomal composition, preferably a vaccine, comprising liposomes formed of liposome forming compounds, containing coentrapped polysaccharide antigen and T-cell dependent protein carrier, such as tetanus toxoid or diphtheria toxin modified to render it non-toxic. The invention is of use in the production of vaccines againstor

Growing community of inventors

Leiden, Netherlands

Jan Wouter Drijfhout