Wyeth Holdings Corporation

De Staat Der Nederlanden, Vertegenwoordigd Door De Minister Van Welzijn,

De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur

De Staat Der Nederlanden

Jan T Poolman

Peter Hoogerhout

Peter Andre Van Der Ley

Peter R Paradiso

Robert C Seid, Jr

Emmanuel J H J Wiertz

John Edward Heckels

Ian Nicholas Clarke

Constant A Van Boeckel

Eduard C Beuvery

Jacobus H Van Boom

Adolf Evenberg

Outer-membrane vesicles, Class 1 outer membrane proteins offragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease.

Recombinant microorganism expressing meningococcal class 1 outer membrane protein

Outer-membrane vesicles, Class 1 outer membrane proteins of, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease.

Meningococcal class 1 outer-membrane protein vaccine

Immunogenic meningococcal LPS and other membrane vesicles and vaccine

The invention relates to new oligosaccharides comprising the structure (D-ribose-D-ribitol-phosphate).sub.m, (D-ribitol-phosphate-D-ribose).sub.m or (phosphate-D-ribose-D-ribitol).sub.m, m being 2,3,4 . . . 19 or 20, to immunogens containing such oligosaccharide, to vaccines containing such immunogens and to methods for preparing such oligosaccharides, immunogens and vaccines. The vaccine is very suitable for treating infections caused by Haemophilus influenzae type b.

Oligosaccharides, immunogens and vaccines, and methods for preparing

Growing community of inventors

Broek in Waterland, Netherlands

Jan T Poolman