Boehringer Mannheim Gmbh

Jan Strejcek

Josef Maier

Manfred Gloger

Sebastian Heimerl

Albert Stumpf

Detlef V Hoerschelmann

A process for obtaining D-2-(6-methoxy-2-naphthyl)-propionic acid from a mixture of D- and L-2-(6-methoxy-2-naphthyl)-propionic acid lower alkyl esters is provided by asymmetric hydrolysis of the L-ester with a microbial enzyme, separation of the 2-(6-methoxy-2-naphthyl)-propionic acid from the D-2-(6-methoxy-2-naphthyl)-propionic acid lower alkyl ester and saponification of the latter, wherein the saponification is carried out enzymatically with esterase from hog liver or from Pleurotus ostreatus.

Process for obtaining D(+)-naproxen

An immersion dialyzer which comprises a removable dialysis head including a membrane holder, at least one inlet canal and a return canal. A holder tube is removably connectable to the dialysis head and includes therein at least one inlet pipe removably connectable to the inlet canal and a return pipe removably connectable to the return canal. A removable membrane is stretchable over the dialysis head, and a closure is provided for the holder tube.

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Iffeldorf, Germany

Jan Strejcek