Biosensor Applications Sweden Ab

Attana Ab

Attana

Jan Smith

Teodor Aastrup

Per Månsson

Henrik Anderson

Henrik Andersson

Kjeld Jensen

Per M&aring;nsson

Ann-Charlotte Hellgren

Per Maansson

A piezoelectric resonator for use in a sensor arrangement for detecting or measuring an analyte in a medium, comprises a quartz crystal plate, having a first crystal surface and a second crystal surface. The first crystal surface is provided with a first electrode, which has a surface area of less than 15 mmand the second crystal surface is provided with a second electrode. The first electrode may have a rectangular surface shape. A flow cell for use in an apparatus for detecting or measuring an analyte in a medium, comprises walls that form a sensing chamber together with the resonator, and inlet and outlet openings for leading a fluid through the sensing chamber. A part of the resonator constitutes one of the walls of the sensing chamber and is arranged such that the first electrode is situated inside the sensing chamber.

Piezoelectric resonator

A piezoelectric sensor arrangement for analysis of fluid samples includes a signal source, a measuring device and a docking system. The sensor arrangement comprises a first part capable of receiving a sensor element that exposes a piezoelectric quartz crystal, a second part comprising fluid channels for the sample and a flow cell element, which preferably is removable and which comprises a recess, and inlet and outlet fluid channels for leading a fluid through the recess. The first and second parts are movable in relation to each other between a closed position and an open position and are arranged such that in the closed position the recess of the flow cell element is sealingly covered by the piezoelectric quartz crystal so that a flow cell is formed by the flow cell element and the quartz crystal.

Piezoelectric sensor arrangement

A system, device and method for detection of several individual analytes in a test solution aliquot () with an array of individually operated piezoelectric crystal microbalances are described. The system comprises a connecting station () that receives a plurality of individually specific piezoelectric crystal microbalance flow-trough cells (), each containing a piezoelectric crystal () carrying electrodes () and a coating () exposing a first member of an interaction pair specific for an individual analyte being a second member of the interaction pair. Flowing means () flows a solution () and the test solution aliquot () to and through a cell compartment of each of the cells () via the connecting station (). Power and measurement means () oscillate the piezoelectric crystal(s) (). A change in oscillating characteristics of the crystal(s) (), following interaction between the first and second members of the interaction pair, detects presence of the individual analyte(s). Further, disposable flow cells () for use in an array of individually operated piezoelectric crystal microbalances () is described.

System, device and method for detection of several individual analytes in a solution, and a disposable flow cell for use therein

An apparatus () and a method for concentrating and transferring volatile compounds contained in a sample on a detachable solid support () into a liquid for subsequent detection and/or analysis of the volatile compounds, are described. The apparatus comprises a holder () for the solid support (), means () for transporting the holder () to a heating position on a heatable plate (), an enclosed space-creating arrangement comprising the heatable plate () attached to a movable housing (), the holder (), the solid support (), a funnel () on the solid support (), and inside the funnel () a chilled member (), means inside the housing () for heating the heatable plate () to evaporate the volatile compounds which then are condensed on the chilled member (), means () for transporting the chilled member () from a cooler () to the inside of the funnel () and from there to a position () where condensed compounds are removed from the chilled member () into a liquid.

Transfer of a sample from a solid support into a liquid

Piezoelectric sensor

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Stockholm, Sweden

Jan Smith