Pacesetter, Inc.

St. Jude Medical, Cardiology Division, Inc.

Jan Mangual

Wenwen Li

Louis-Philippe Richer

Yun Qiao

Nima Badie

Luke C McSpadden

Chunlan Jiang

Fady Dawoud

Cyrille Casset

Craig Markovitz

Chaoyi Kang

Donald Lee Hopper

Theodore Paul Dale

Nikolaos Politis

Saurabh Datta

Luc Soucie

Luke C Mcspadden

Techniques are provided for guidance for navigation and positioning of intravascularly delivered devices. A medical navigation system includes a delivery device comprising a catheter, an intravascularly delivered device configured to be releasably disposed in the catheter for deployment at a target site of a patient, and a navigation computer system. The intravascularly delivered device includes a plurality of electrodes including at least one indicator electrode and at least one reference electrode configured to not contact tissue when the intravascularly delivered device is deployed at the target site. The navigation computer system is configured to be electrically coupled with the plurality of electrodes. The navigation computer system controls a drive source to transmit current to the plurality of electrodes, collects electrode data corresponding to the plurality of electrodes, monitors impedance corresponding to the indicator electrode, and determines that the indicator electrode has made contact with tissue.

Guidance for navigation and positioning of intravascularly delivered devices

Certain embodiments of the present technology described herein relate to detecting atrial oversensing, characterizing atrial oversensing, determining when atrial oversensing is likely to occur, and or reducing the chance of atrial oversensing occurring. Some such embodiments characterize and/or avoid atrial oversensing.

Implantable medical systems and methods used to detect, characterize or avoid atrial oversensing within an IEGM

Described herein are implantable medical devices and systems, and methods for use therewith, for reducing T-wave oversensing and arrhythmia undersensing that occur due to inappropriate filtering of a signal indicative of cardiac electrical activity. A method includes obtaining a signal indicative of cardiac electrical activity, and using a first bandpass filter to produce a first filtered version thereof, using a second bandpass filter to produce a second filtered version thereof, wherein the first bandpass filter passes frequencies within a first frequency range, and the second bandpass filter passes frequencies within a second frequency range that is wider than the first frequency range. The method also includes selectively changing from using the first filtered version of the signal to monitor for a VS event, to using the second filtered version of the signal to monitor for a VS event, based on first criteria, and vice versa, based on second criteria.

Implantable medical devices, systems and methods for reducing T-wave oversensing and arrhythmia undersensing

Described herein are methods, devices, and systems that identify ventricular sensed (VS) events from a signal indicative of cardiac electrical activity, such a far-field EGM or ECG signal, and monitor for an arrythmia and/or perform arrythmia discrimination based on the VS events. Beneficially, such embodiments reduce the probability of double-counting of R-wave, or more generally, of oversensing VS events, and thereby provide for improved arrythmia detection and arrythmia discrimination.

Robust ventricular sensing of far-field EGM or ECG signals that avoids oversensing of ventricular sensed events

Methods, systems, and devices that are used for improving cardiac resynchronization therapy (CRT) are described herein. Such a method can include, for each set of pacing parameters, of a plurality of sets of pacing parameters, performing CRT using a set of pacing parameters and simultaneously therewith sensing a plurality of intracardiac electrograms (IEGMs) using different combinations of implanted electrodes. Additionally, for each set of pacing parameters, of the plurality of sets of pacing parameters, the method includes producing a respective reconstructed multi-lead surface electrocardiogram (ECG) based on the plurality of IEGMs that were sensed while CRT was performed using the set of pacing parameters. The method also includes analyzing the reconstructed multi-lead surface ECGs that were produced for the plurality of sets of pacing parameters, and based on results thereof, identifying a set of pacing parameters to be use for further CRT.

Methods, system and device for improving cardiac resynchronization therapy (CRT)

Certain embodiments of the present technology described herein relate to detecting atrial oversensing in a His intracardiac electrogram (His IEGM), characterizing atrial oversensing, determining when atrial oversensing is likely to occur, and or reducing the chance of atrial oversensing occurring. Some such embodiments characterize and/or avoid atrial oversensing within a His IEGM. Other embodiments of the present technology described herein relate to determining whether atrial capture occurs in response to His bundle pacing (HBP). Still other embodiments of the present technology described herein relate to determining whether AV node capture occurs in response to HBP.

Implantable medical systems and methods used to detect, characterize or avoid atrial oversensing within a His IEGM

Implantable medical systems and methods for use therewith that detect atrial capture and AV node capture responsive to his bundle pacing

Systems and methods for identifying potential ablation sites using electrical parameter data are provided. A method includes geometrically isolating an arrhythmogenic substrate in a three-dimensional geometry. The method further includes generating a first cumulative map from a first dataset including electrical parameter data for each vertex in the isolated arrhythmogenic substrate, and generating a second cumulative map from a second dataset including additional data for each vertex. The method further includes generating a third cumulative map from the first and second cumulative maps, and displaying the third cumulative map on the three-dimensional geometry to facilitate identifying potential ablation sites.

Systems and methods for identifying ablation locations using electrical parameter data

The present disclosure is directed to merging data acquired from differently configured catheters on a common map. In use, physical characteristics of catheters influence recorded electrical signals/responses such that differently configured catheters (e.g., different electrode sizes, shapes, materials, spacings, etc.) may record different responses to measurements taken at the same location in response to the same excitation signal. To allow merging of data from differently configured catheters in a common map, the present disclosure applies a corrective coefficient or transfer function to the recorded electrical signals of one or both catheters to counter-balance variable influences of catheter specific characteristics on recorded signals.

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Rho, Italy

Jan Mangual