Evonik Roehm Gmbh

Evonik Operations Gmbh

Evonik Degussa Gmbh

Evonik Rohm Gmbh

Kaneka Belgium N.v.

Kaneka Belguim N.v.

Jan Hendrik Schattka

Gerd Loehden

Christian Meier

Florian Hermes

Kathrin Nollenberger

Thomas Riermeier

Rainer Lomoelder

Dirk Hoppe

Markus Pridoehl

Guido Zimmermann

Holger Kautz

Manfred Assmus

Marita Kaufmann

Manfred Braum

Wernfried Heilen

Herbert Jung

Stephan Fengler

Markus Pridöhl

Winfried Belzner

Rainer Lomölder

Christoph Nacke

Sebastian Roos

Ursula Rausch

Christian Moers

Thomas Dassinger

Gerd Löhden

Andreas Huether

Thomas Endres

Hedi Krachtus

Fabian-Pascal Schmied

Jessica Del Rosario Ferrand

Isabel Wahl

Elisabeth Ghulam

Alena-Davina Max

Manuel Seibel

Thomas Eurich

Michael Wolff

Rene Leubert

Thomas Matten

Andreas Hüther

René Leubert

Rebecca Zmarzly

Florian Matthess

Hans-Jürgen Geyer

A process can prepare a bio-resorbable polyester as a granulate or powder by bulk polymerization of one or more monomer(s). The process involves a) filling a monomer granulate, containing the one or more monomer(s), into a container; b) adding a polymerization catalyst and a chain length moderator on top of the monomer granulate; c) adding further monomer granulate on top; d) closing the container; e) carrying out a polymerization reaction in the closed container at a temperature in the range of 50° C. to 170° C., wherein a solid polymer in the form of a polymer block is formed; f) removing the polymer block from the container; and g) comminuting the polymer block to a granulate or powder; wherein the container is an unstirred container, wherein steps b) and c) are carried out once or are repeated, and wherein steps a) to e) are carried out under inert atmosphere.

Process for preparing a resorbable polyester as a granulate or powder by bulk polymerization

A novel methacrylic copolymer contains units derived from at least one alkyl methacrylate and methacrylamide. The units derived from methacrylamide are present in at least 34 wt.-%, based on the total weight of the methacrylic copolymer. A method can be used for preparing these novel methacylic copolymers. Pharmaceutical compositions, nutraceutical compositions, coated pharmaceutical or nutraceutical dosage forms, as well as nano- or microparticles can contain the methacrylic copolymer. The methacrylic copolymer can be used as a coating, as a carrier, and as a matrix for an amorphous solid dispersion.

Methacrylate copolymer and compositions comprising it

The invention relates to a coating composition suitable for the coating of a pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein either the core of the core/shell polymer composition is formed by a water-insoluble, not cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer or vice versa.

Coating composition suitable for pharmaceutical or nutraceutical dosage forms

The invention discloses a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the gastric resistant coating layer comprises at least 30% by weight of a (meth)acrylate copolymer comprising polymerized units of 10 to 40% by weight of acrylic or methacrylic acid, 10 to 80% by weight of a C- to C-alkyl ester of acrylic or methacrylic acid and optionally 0 to 60% by weight of another vinylic monomer, whereby the release of the pharmaceutical or nutraceutical active ingredient is not more than 10% under in-vitro conditions at pH 1.2 after 2 hours in medium according to USP with and without the addition of 20% (v/v) ethanol.

Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol

The invention relates to a coating composition suitable for the coating of pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein the core of the core/shell polymer composition is formed by a water-insoluble, cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer.

The invention relates to plastisols which even without the addition of adhesion promoters exhibit high adhesion to metallic and cathodically deposition-coated substrates.

Adhesive agents for plastisols

The invention relates to pulverulent core/shell polymers for the preparation of a plastisol, which have surprisingly low water absorption. The invention further relates to the plastisol pastes which are prepared from these polymers and likewise have low water absorption and additionally possess good storage stability, good mechanical properties and good plasticizer compatibility. The core/shell polymers consist of latex particles having a primary particle size of at least 250 nm, the core consisting of methyl methacrylate, (meth)acrylic esters with Cto Cor aromatic alcohol radicals and optionally further monomers, and the shells(s) comprising, in addition to these components, also amides of (meth)acrylic acid and/or amine-substituted alkyl esters of (meth)acrylic acid.

Low water-absorption plastisol polymers

The present invention relates to the use of different-sized polymeric microparticles in hydraulically setting building material mixtures for the purpose of enhancing their frost resistance and cyclical freeze/thaw durability.

Additive building material mixtures containing different-sized microparticles

The invention relates to a method of bonding different materials of construction using hybrid materials comprising nanoscale, superparamagnetic, ferromagnetic, ferrimagnetic or paramagnetic powders enveloped or in part not enveloped by poly(meth)acrylates, and to their use.

Method of bonding materials of construction using nanoscale, superparamagnetic poly(meth)acrylate polymers

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Hanau, Germany

Jan Hendrik Schattka