Other

Breas Medical Ab

Desitin Arzneimittel Gmbh

Stenlof, Kaj

Grote, Ludger

Hedner, Jan

Kaj Stenlof

Jan Hedner

Ludger Grote

Cereus Pharma Ab

Mikael Tiedje

Kaj Stenlöf

Lars Sjöström

Henrik Bergfalk

Petter Knagenhjelm

Ove Eklund

Hans Petter Knagenhjelm

Holger Kraiczi

Lutger Grote

There is provided for novel therapy of sleep apnea that involves administering the drug sultiame to the patient.

Sultiame for the treatment of sleep apnea

A method for treating snoring, sleep apnoea and other forms of sleep disordered breathing involves administration to a patient of a therapeutically effective amount of topiramate over an appropriate period of time, such as a period substantially coinciding with the sleep period of a patient. A useful route of administration is per os. Also disclosed is the use of topiramate for the diagnosis of snoring, sleep apnoea and other forms of sleep disordered breathing.

Method of treating sleep disordered breathing using topiramate

A method of treating or preventing Obstructive Sleep Apnea (OSA) comprises the administration of a pharmacologically effective amount of zonisamide to a patient in need thereof, with the proviso that OSA caused by external mechanical obstruction of the airways, such as by mucus, is excluded. Also disclosed is the use of zonisamide for the manufacture of a medicament useful in the treatment; a protective patch comprising zonisamide and a pharmaceutically acceptable carrier for transdermal or transmucosal administration to a person suffering from OSA; and the use of zonisamide for the manufacture of a diagnostic device, kit or composition for the diagnosis of sleep disordered breathing.

Method of treating and diagnosing sleep disordered breathing and means for carrying out the method

A method for the detection and treatment of disordered breathing during sleep employs an artificial neural network (ANN) in which data related to breathing gas flow are analyzed. A respiratory circuit is established by connecting the patient to a continuous positive airway pressure (CPAP) system with pressurized breathing gas supply, the gas flow in the circuit is periodically sampled, one or several cepstrum parameters distinctive of various breathing patterns are periodically calculated; the parameter values are periodically fed to an ANN trained to recognize breathing patterns characteristic of sleep disordered breathing and are analyzed in the network, the CPAP pressurized breathing gas supply is controlled in response to the ANN output. Also disclosed is a corresponding apparatus.

Auto CPAP

Methods of treating and diagnosing sleep disordered breathing and means

Growing community of inventors

Göteborg, Sweden

Jan Hedner