Biotronik Mess-und Therapiegeraete Gmbh & Co Ingenieurbuero Berlin

Biotronik Se Co. Kg

Biotronik Mess-und Therapiegerate Gmbh & Co.

Biotronik Mess- Und Therapieger&auml;te Gmbh & Co. Ingenieurb&uuml;ro Berlin

Jan H Meier

Erhard Flach

Tobias Breskot

Eric Fourni&eacute;

Eric Fournié

An electrostimulator having electrode connections which are to be connected, at least at times, to a stimulation unit and to a detection unit of the electrostimulator. The stimulation unit is adapted to generate electrostimulation pulses for the stimulation of body tissue and to deliver the electrostimulation pulses to at least one of the electrode connections. The detection unit is adapted to detect successful stimulation of body tissue on the basis of an electrical signal occurring at least one of the electrode connections. The electrostimulator is adapted to record an electrical signal representative of an intracardial electrocardiogram by way of the at least one electrode connection. Arranged between the electrode line connection and the detection unit is a high pass filter with a lower limit frequency of greater than 100 Hz, and the detection unit is adapted to evaluate the high pass-filtered electrical signal.

Electrostimulator

Method for calculating the heart rate variability for being applied in an ECG monitor, and ECG monitor comprising an appropriate calculation program

A capture-detection cardiac pacemaker wherein a stimulation success can be reliably detected immediately after stimulation pulse output. The cardiac pacemaker according to this invention generally includes at least one stimulation electrode arranged in the region of the heart designed to output stimulation pulses to the heart, and a control unit connected to a pulse generator for controlling the stimulation pulse output. The control unit is connected to a sensor arranged at the myocardium for checking stimulation success at the heart by detecting the myocardial impedance pattern immediately after a stimulation pulse output and still within the diastolic phase of the heart, and controlling the stimulation pulse output based thereon.

Pacemaker capable of sensing impedance changes in myocardial tissue

A neural electrode arrangement comprises an elastically deformable carrier body defining a cylindrical internal space therein, and at least one electrode which is fixedly connected to the carrier body and which is in peripherally touchingly operative relationship with the internal space in the carrier body. The electrode is formed from an elongated wire coil.

Neural electrode arrangement

A self-calibrating adaptive-rate cardiac pacemaker having a measuring and processing device for measuring the course over time of a physiological variable over a predetermined portion of a heart cycle and for obtaining a course parameter from the course over time, a stimulation parameter determining device downstream of the measuring and processing device and controlled by a sequence controller for determining a stimulation parameter value, in particular the adaptive stimulation rate, a body sensor connected to one input of the stimulation parameter determining device, for detecting an exertion variable, whose signal is used jointly with the course parameter to determine the stimulation parameter value, and a stimulator unit for generating and outputting stimulation pulses at the determined stimulation parameter value. The measuring and processing device is arranged to obtain a plurality of different values of the course parameter as a function of at least one setting point in a calibration phase, and the stimulation parameter determining device has a stimulation parameter calculating device connected downstream of the measuring and processing device for calculating a plurality of stimulation parameter selection values, each as a function of one value for the course parameter, a reference parameter calculating device connected downstream of the body sensor, for calculating an activity -determined reference parameter value, a comparator unit connected on the input side to the stimulation parameter calculating device and to the reference parameter calculating device, for comparing the parameter selection values with the reference parameter value, and a decision-making device connected on the input side to the output of the comparator unit, for selecting one of the setting point values of the measuring and processing device, associated with the parameter selection values, as current setting point value for further control of the pacemaker, substantially on the basis of the course parameter as the outcome of the comparison.

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Uttenreuth, Germany

Jan H Meier