Universitât Bern

Jan Burian

Joachim Frey

Michael A Kuzyk

Julian C Thornton

Peter Kuhnert

Tracy A Thornton, Legal Representative

Martin Braun

Katja Stuber

A protein toxin namedexoenzyme T (AexT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a novel Calcium (or other cation concentration) dependent promoter of. Also disclosed are diagnostic, preventive, and therapeutic techniques, including the preparation of bacterin vaccines based on AexT for inducing immunity againstinfections.

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Disclosed is a newly identified and characterized type III secretion system in. The invention also encompasses the use of components of the novel secretion system in immunoprotection againstinfection, as well as other diagnostic and therapeutic uses thereof.

A novel protein toxin namedexoenzyme T (AexT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a novel Calcium (or other cation concentration) dependent promoter ofAlso disclosed are diagnostic, preventative, and therapeutic techniques, including the preparation of traditional, recombinant, and improved bacterin vaccines based on AexT for inducing immunity againstinfections.

A protein toxin namedexoenzyme T (AcxT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a Calcium (or other cation concentration) dependent promoter of. Also disclosed are diagnostic, preventive, and therapeutic techniques, including the preparation of bacterin vaccines based on AexT for inducing immunity againstinfections.

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Victoria, Canada

Jan Burian