Other

Jan Andersson

Lars Bertil Nilsson

Judah M Folkman

Kurt Paulsson

Lars Holmgren

Anna-Lena Spetz-Holmgren

Valter Swedberg

Benjamin Trok

The present invention relates to a method of of transferring genomic DNA from apoptotic bodies to engulfing cells, wherein DNA is transferred from a donor cell to a recipient cell. More specifically the method includes providing somatic donor cells comprising desired DNA; generating apoptotic bodies of said donor cells; incubation of the apoptotic bodies with engulfing recipient cells under biological conditions allowing uptake of DNA from the apoptotic bodies by said recipient cells; and optionally selecting recipient cells which have integrated DNA from the apoptotic bodies. The present method is useful in various pharmaceutical applications, such as in vaccine preparations and gene identification procedures. Further, the present invention also relates to a method of preventing and/or treating a clinical condition in a patient, which comprises isolating cells comprising genomic DNA; generating apoptotic bodies of said isolated cells; incubation of said apoptotic bodies with engulfing recipient cells under biological conditions allowing uptake of DNA from the apoptotic bodies, optionally, selecting cells containing DNA originating from the isolated cells; and administering cells in a pharmaceutically acceptable carrier to the patient, thus enabling a protective and/or therapeutic reaction against the clinical condition.

Method of DNA transfer

Process and apparatus for driving away adsorbates

A finger pen is provided which may be removably attached to a finger such that the pen is held in a prone position by which is meant that the pen is held in place with the palm of the hand turned downward facing the surface which is to be written upon.

Finger pen

Method and apparatus for the separation of one or more agents

The central unit of a PABX telephone system includes an associated computer unit that operates to provide visual information to an operator when calls to an extension in the system are to be intercepted. The associated computer unit includes a memory into which a subscriber to the system enters information relating to the reason his calls are to be intercepted, or the like. Any calls to the intercepted extension are routed to the operator, who is simultaneously provided with a visual display of the information stored in the computer memory.

Intercept information display for a private automatic branch exchange

A clamping force of given strength is directed at right angles to a rectangular piece of plastic sheeting whose width and length are somewhat greater than that of a cupboard door with the piece of plastic sandwiched between the door and an evenly heated supporting plate which is maintained at constant temperature of at least 50.degree. C., and the projecting marginal edges of the plastic sheeting are stretched and subsequently pressed against the surface portion on the rear side of the cupboard door preheated with contact glue. The applied clamping force must be sufficient to prevent the portion of sheeting from being pulled out from between the plate and the cupboard door front while permitting that sheet portion to be stretched and extended along with the marginal portion through which the stretch force is exerted, but the force may not be so excessive that the stretching or extension of that sheet portion is prohibitive.

Growing community of inventors

Deje, Sweden

Jan Andersson