Ryogen LLC

University of Miami

Other

Corning Glass Works

Ventrex Laboratories, Inc.

Kyoger, LLC

James W Ryan

Alfred Chung

Edward H Yonkers

James E Woiszwillo

Haralambos P Gavras

Roger N Piasio

Terry Joe Curtis Sprinkle

The invention is directed to isolated genomic polynucleotide fragments that encode human carboxypeptidase M and human mouse double minute 2 homolog, vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human carboxypeptidase M and human mouse double minute 2 homolog and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Identification of human mouse double minute 2 homolog nucleotide sequences

Provided are isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Identification of POLD2 sequences

Isolated glucokinase genomic polynucleotide fragments from chromosome 7

Modulation of human mouse double minute 2 homolog activity

Provided herein are isolated genomic polynucleotide fragments from the p15 arm of chromosome 11 and methods of use.

Identification of isolated genomic nucleotide fragments from the p15 region of chromosome 11 encoding human cluster of differentiation antigen 81 and variants thereof

Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human and tumor suppressing subtransferable candidate 4 (TSSC4) and methods of use.

Identification of isolated genomic nucleotide fragments from the p15 region of chromosome 11 encoding human tumor suppressing subtransferable candidate 4 (TSSC4) and variants thereof

Isolated genomic polynucleotide fragments from the p15 region of isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human tumor suppressing subtransferable candidate 4 (TSSC4)

Isolated genomic polynucleotide fragments from the p15 region of chromosome 11

Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human SMS3 (SMS3) and methods of use.

Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human SMS3

Provided herein are isolated genomic polynucleotide fragments from the p15 arm of chromosome 11 encoding HASH2 and methods of use.

Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human achaete-scute homolog 2 (HASH2)

Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human ribosomal protein L26 (RIBO26) and methods of use.

Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human ribosomal protein L26 (RIBO26)

Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human tumor suppressing subtransferable candidate 6 and methods of use.

Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human tumor suppressing subtransferable candidate 6 (TSSC6)

The invention is directed to isolated genomic polynucleotide fragments that encode human resistin and human syntaxin binding protein 2, vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human resistin and human syntaxin binding protein 2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Isolated 3'-noncoding genomic human resistin polynucleotide fragments

Isolated genomic polynucleotide fragments from chromosome 12 that encode human carboxypeptidase M

The invention is directed to isolated genomic polynucleotide fragments that encode human SNARE YKT6, human glucokinase, human adipocyte enhancer binding protein (AEBP1) and DNA directed 50 kD regulatory subunit (POLD2), vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain SNARE YKT6, human glucokinase, AEBP1 protein and POLD2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder.

Growing community of inventors

Miami, FL, United States of America

James W Ryan