University of California

James W Golden

Michael D Burkart

Ewa Lis

Steve A Kay

Susan Golden

Hugo Gramajo

Dawn M Adin

Julia Roulet

Michael Melnick

Jeffrey Mindrebo

Arnaud Taton

Ana Arabolaza

Provided herein, inter alia, is a modular-functional technology for the expression of a functional heterologous polyketide synthases (PKS) system in a photosynthetic cyanobacteria.

Engineering polyketide synthase in cyanobacteria

Provided herein are methods and compositions for the production of renewable fatty acids from photosynthetic prokaryotic microorganisms, such as a blue green algae, any specie of the phylum Cyanophyta, a chloroplast of a green algae and/or a Cyanobacterium. Engineered or natural strains of these organisms or organelles can be used to produce both saturated and unsaturated fatty acids with variable chain length specificity from 8-18 carbons. The fatty acids can then be secreted into the culture medium, allowing for rapid, continuous and efficient separation of fatty acid product without harvesting of cell mass.

Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms

Growing community of inventors

Del Mar, CA, United States of America

James W Golden