Biosciences Corporation of Texas

James W Freeman

Harris Busch

Rose K Busch

Tumor nucleoli were treated with polyclonal antisera to normal human tissue nucleoli to block determinants common to tumor and normal tissue nucleoli. Immunization of mice with these immune-complexes resulted in the development of a monoclonal antibody (FB2) to a novel nucleolar proliferation associated antigen which has a molecular wei

Detection of human cancer cells with antibodies to human cancer

Specific common nucleolar antigens are found in a broad range of human malignant tumor specimens and have been isolated, extracted and purifed. Monoclonal antibodies specific to one of these nucleolar antigens (p145) are harvested from mouse ascites or culture supernatant and used for detection of human

Growing community of inventors

Houston, TX, United States of America

James W Freeman