Beth Israel Deaconess Medical Center, Inc.

Duke University

Los Alamos National Security, LLC

University of Pennsylvania

University of Alabama

Oxford University Innovation Limited

Triad National Security, LLC

Los Alamos Security, LLC

U. of Alabama at Birmingham Research Foundation

James Theiler

Simon J Perkins

Barton F Haynes

Bette T Korber

Beatrice H Hahn

William M Fischer

Norman L Letvin

Karina Yusim

Carla L Kuiken

Tanmoy Bhattacharya

Dan H Barouch

Drew Weissman

Tomas Hanke

Bette T M Korber

Louis Picker

Klaus Frueh

Bette Tm Korber

Emily Marshall

Eric Bruening

Immunogenic compositions and methods of their use in eliciting immune responses to coronaviruses, such as SARS-CoV-2 are provided.

Conserved region T cell vaccines for coronavirus and methods of use

The disclosure generally relates to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same.

Nucleic acids encoding mosaic HIV-1 gag proteins

The present invention relates to mosaic HIV-1 group M Gag sequences and to a composition comprising same.

Human immunodeficiency virus type 1 clade M mosaic gag polypeptides

The present invention relates to mosaic clade M HIV-1 Nef polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins

A distribution-based anomaly detection platform is described that identifies a non-flat background that is specified in terms of the distribution of the data. A resampling approach is also disclosed employing scrambled resampling of the original data with one class specified by the data and the other by the explicit distribution, and solving using binary classification.

Anomalous change detection in imagery

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Los Alamos, NM, United States of America

James Theiler