University of Dundee

The Institute for Ethnomedicine

Brain Chemistry Labs

James S Metcalf

Paul Alan Cox

Sandra Banack

Rachael Dunlop

Geoffrey A Codd

Presented herein are compositions comprising L-serine, or a precursor, derivative or conjugate thereof, and a non-toxic metal, such as zinc. Compositions disclosed herein can be used for the prevention and treatment of neurodegenerative diseases, or related symptoms thereof.

Compositions comprising a metal and L-serine, and uses thereof

An immunoassay for screening a sample to detect the presence of &#x3b2;-N-methylamino-L-alanine (BMAA) is disclosed. Antibodies specific for BMAA are disclosed. Antibodies that bind to BMAA on immunoblots are disclosed. Immunoassays and kits to detect the presence of BMAA in a sample by contacting the sample with an antibody that binds to BMAA, and detecting the antibody bound to the sample, are disclosed. Immunoassays and kits for screening for the presence of BMAA in a subject by analyzing a tissue sample obtained from the subject to detect the present of BMAA in the tissue sample, where the presence of BMAA in the tissue sample indicates exposure of the subject to an environmental source of BMAA, are disclosed. Immunoassays and kits for detecting an environmental source of BMAA, by screening an environmental sample to detect the presence of BMAA in the sample, wherein the presence of a detectable amount of BMAA in the sample indicates the sample is an environmental source of BMAA, are disclosed.

Immunoassay for detection of neurotoxic amino acid associated with neurological disorders

Growing community of inventors

Jackson, WY, United States of America

James S Metcalf