Applied Bioscience

Other

Seroptix, Inc.

James S Harrison

Paul Terence Wertlake

Yongwu Yang

Joseph M Canter

Wanglong Zhou

Michael A Greenwald

Melvin P Ehrlich

Victor S Sapirstein

Michael Y Lu

Omanand Koul

Eugene Katsman

A quantitative process for monitoring female fertility cycle wherein the process involves directing a laser beam, preferably generated by a diode laser, onto an area of a slide containing an air-dried sample of a female body fluid. The diffraction pattern resulting from the sample is detected by a two-dimensional photo diode array and analyzed by a microprocessor. If a ferning pattern exists, such pattern will generate a characteristic structure in the diffraction pattern which is then detected by the photo diode array. If no ferning occurs, the corresponding diffraction pattern will be structureless. The microprocessor is programmed with an algorithm to produce a quantitative index of ferning indicating quantitatively the ferning level. Preferably, a plurality of spots on the sample are measured to determine the ferning level at each spot, and the microprocessor then makes a final determination as to final ferning level on the basis of the test results of all of the spots. This significantly increases the reliability of the final test result, since a defect at one test spot or anomaly of one test result will not be fatal to the final result.

Apparatus and method for monitoring ovulation

A fixative composition for histological, cytological, immunological and proteinaceous preparations comprising a mixture of pyrrolid-2-one, a polyol, a urea and a zinc salt of a non-oxidizing organic or inorganic acid. Also disclosed are devices utilizing such compositions.

Composition for diagnostic reagents

Preservative and fixative preparations for biological systems

A superior and extremely rapid histological staining method is described in which frozen tissue is briefly immersed in an aqueous solution comprising trichloroacetic acid, zinc chloride and formaldehyde and then in a second solution comprising hematoxylin. The tissue can be further counterstained if desired. Also disclosed are improved fixatives useful in this and other histological techniques.

Tissue staining method and composition

A system for the transferral, freezing, storage and processing of liquids with a minimum of contamination is described. The components of the system include a hollow disc-shaped vessel of special construction which permits rapid freezing at extremely low temperatures, a pierceable, resilient sealing member on the ports of the disc-shaped vessel and a pointed cannular needle which is protected from contamination prior to use and operable to pierce the sealing member free of any contamination.

Freeze storage container system

An apparatus for separating particles from a fluid comprising a housing, means for flowing a fluid through said housing, a plurality of parallel perforated plates supported in said housing spaced from one another in the direction of fluid flow, the plates being effective to accelerate the fluid as it passes through each plate, and a sample-holder immediately downstream of each perforated plate, the fluid flowing through each said plate onto its associated sample-holder and thence around the sample-holder to the next downstream plate, the inner wall of the housing being spaced from the path of fluid flow at least sufficient to substantially avoid contact with fluid flowing along the path.

Aerosol analyzer

Growing community of inventors

Ringwood, NJ, United States of America

James S Harrison