Astra Aktiebolag

Eastman-kodak Company

Astrazeneca Ab

Fisons Ltd.

Astra Pharmaceuticals Limited

James Russell Matz

William Calvin Shakespeare

James Edwin MacDonald

Harald Baumann

Udo Dwars

Mathias Jarek

Christopher D Simpson

Robert John Murray

Domenico Balbinot

James Macdonald

Deepak Shukla

William C Shakespeare

Ronald C Griffith

James J Napier

Kevin P Dockery

Jerome Robert Lenhard

Christopher T Brown

Koji Hayashi

Alan C Tinker

Peter Richard Hamley

Masamichi Kamiya

Satoshi Ishii

Yoshiaki Sekiguchi

James E MacDonald

A negative-working infrared radiation-sensitive lithographic printing plate precursor can be imaged and developed on-press to provide a lithographic printing plate. Such precursor has an initiator composition that contains compound A of Structure (I) and one or more compounds collectively as compound B of Structure (II) or Structure (III): wherein R, R, R, R, Rand Rare independently alkyl groups each having 3 to 6 carbon atoms; at least one of Rand Ris different from Ror R; the difference of total number of carbon atoms in Rand Rand the total number of carbon atoms in Rand Ris 0, 1, or 2; the difference of total number of carbon atoms in Rand Rand the total number of carbon atoms in Rand Ris 0, 1, or 2; and X, Xand Xare the same or different anions.

Negatively-working lithographic printing plate precursor and method

A lithographic printing plate precursor comprises an imageable layer comprising a free radically polymerizable component, an initiator composition capable of generating free radicals upon exposure to imaging infrared radiation, an infrared radiation absorbing dye that is defined by Structure (I) shown in the disclosure, which dyes comprise one or more ethylenically unsaturated polymerizable groups in an organic group that is attached to the methine chain. These infrared radiation absorbing dyes exhibit a reduced tendency to crystallize in the imageable layers in the presence of tetraaryl borate counter anions and therefore provide improved shelf life.

Negative-working lithographic printing plate precursors with IR dyes

A process for forming an aryl-aryl bond comprises the step of reacting an arene hydrocarbon compound with either (1) an organic oxidant selected from the group consisting of a quinone, a quinone imine, a quinone diimine, and a nitroarene, or (2) an oxidizing salt selected from the group consisting of a triarylaminium salt, an oxonium salt, and a nitrosium salt, or (3) a hypervalent iodine compound, each in the presence of a Br&#xf6;nsted or Lewis acid.

Synthesis for polycyclic aromatic hydrocarbon compounds

Amidine derivatives as inhibitors of nitric oxide synthase

Compounds

There are provided novel compounds of formula (I) ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.

Amidine and isothiourea derivatives as inhibitors of nitric oxide

There are provided compounds of formula (I), ##STR1## wherein D represents a five membered heterocyclic aromatic ring containing 1 to 4 heteroatoms selected from O, N or S, optionally substituted at a carbon atom by halogen, trifluoromethyl, alkyl C1 to 6, nitro or cyano, and which is connected to the remainder of the compound of formula (I) through a carbon atom; A represents N(X) or CH(--(CH.sub.2).sub.m --NXY); U represents NH, O or CH.sub.2 ; V represents (CH.sub.2).sub.a ; W represents (CH.sub.2).sub.b ; a, b, m, X and Y are as defined in the specification, together with processes for their preparation and compositions containing them. Compounds of formula (I) are nitric oxide synthetase inhibitors and are useful in therapy.

Growing community of inventors

Fairport, NY, United States of America

James Russell Matz