Applied Biosystems, LLC

Applera Corporation

Sutro Biopharma, Inc.

James Rozzelle

Elena Bolchakova

Gang Yin

Christopher James Murray

James F Zawada

Daniel Gold

Alexei M Voloshin

Nathan Uter

The invention provides nucleic acids and polypeptides for nucleic acid polymerases from a thermophilic organism,. The invention also provides methods for using these nucleic acids and polypeptides.

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The invention provides nucleic acids and polypeptides for a nucleic acid polymerase from a thermophilic organism,. The invention also provides methods for using these nucleic acids and polypeptides.

Thermus scotoductus nucleic acid polymerases

The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids.

This invention provides for a novel means of incorporating non-native amino acids into preselected positions of a protein using a cell-free synthesis system. The methods involve the use of non-orthogonal, native isoaccepting sense tRNAs that are encoded by the genetic code. Such methods allow for numerous non-native amino acids to be incorporated through the use of sense codons without having to rely upon orthogonal tRNA-synthetase pairs.

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San Francisco, CA, United States of America

James Rozzelle