Cardiokinetix, Inc.

Boston Scientific Scimed, Inc.

Puracath Medical, Inc.

Acueity, Inc.

Other

Edwards Lifesciences Corporation

Ams Research Corporation

James Raymond Kermode

Miles D Alexander

Michael P Boutillette

Douglas R Murphy-Chutorian

Matthew T Davila

Irene Bing Bie Tan

Alexander K Khairkhahan

Richard L Mueller

Serjan D Nikolic

Charles Martin Schwimmer

U Hiram Chee

Curtis Peter Tom

Julia A Rasooly

Justin Aaron Lance

Michael Rasooly

Ken Arnold

Kester Nahen

Richard L Mueller, Jr

Yumee Gang

Tammy Gravelle

Steven Yihlih Peng

Disclosed herein are devices and methods related to UV disinfection of a transfer catheter during peritoneal dialysis. The transfer catheter comprises a first and second end, the second end comprising a transfer valve. The transfer valve body comprises an inlet, outlet, and a flush hole. The valve core comprises a notch configured to allow fluid flow between the various flow paths. The valve core and body are positioned off axis with respect to the fluid flow path. The transfer catheter can allow for a small volume kill zone, which can minimize the amount of UV required to disinfect the catheter.

Transfer catheter for ultraviolet disinfection

Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.

Devices and methods for delivering an endocardial device

Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.

Ventricular volume reduction

Described herein are devices, systems and methods for delivering an endocardial device. The systems for delivering the device transvascularly may generally include an elongate guide catheter having a proximal end and a distal end; a conical dilator at the distal end of the elongate guide catheter, the conical dilator being removable to enable delivery of the ventricular portioning device; a delivery catheter having a proximal and distal end; an expansion member near the distal end of the delivery catheter and configured to expand a plurality of struts of the partitioning device; and a coupling element configured to deployably secure to a hub of the partitioning device. The systems for delivering the device transapically may generally include an elongate access sheath; an elongate delivery catheter; an expansion member; and a coupling element proximal to the expansion member and configured to deployably secure to a hub of the partitioning device.

An endoscope for an optical fiber provides for inflow and outflow of irrigant. A telescope is included having a field of view directed into a working region. The endoscope defines a 'hooded region' with an extended, blunt tip. The optical fiber fits within the endoscope has a side or end firing tip with an emission surface. A guide element is adapted to movably support the optical fiber in a position spaced away from the working region, and limit lateral movement of the tip without preventing longitudinal and rotational movement. An irrigant flow arrangement operates to direct inflowing irrigant over the emission surface of the tip. The fiber is assembled with a fiber coupler, a handle, a fiber port cap, and a travel limiter fixed to the fiber at a predetermined distance from the tip. The travel limiter cooperates with the endoscope and the fiber port cap to limit longitudinal and rotational movement of the fiber.

Endoscope and optical fiber assembly

Described herein are partitioning devices for reducing ventricular volume that may be secured within a ventricle and separate it into a productive portion and a non-productive portion. The partitioning devices described herein may include a reinforced membrane and may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating an inflatable element on the periphery of the device. All or a region of the non-productive portion formed by these devices may be enclosed within a container or bag. The non-productive portion may be filled with a material, including occlusive materials (e.g., vasoclusive coils). Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region. Also described herein are systems including these devices and methods of using them, which may be suitable for treating patients with heart disease, particularly congestive heart failure.

Sealing and filling ventricular partitioning devices to improve cardiac function

Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.

Methods of treating cardiac arrhythmia

The invention described herein provides for methods and devices for treating tissues, and in particular, ischemic heart tissue. Preferred devices includes tools integrating both injury and treatment effectors in a single unit. An optional third effector provides an effector for marking locations on a tissue surface that have been visited by the device. Methods are provided in which a target tissue is identified, injury sites are created at known locations, and therapeutic-substance is infused at known locations different than the injury sites.

Method and apparatus for treating ischemic tissue

Method and apparatus for treatment of atrial fibrillation

A biopsy device suitable for collecting cells from a mammary duct is provided. The device is suitable for conducting brushing biopsy and tissue excision procedures. The device comprises a sheath that is rotatable about a longitudinal axis. The device further comprises an endoscope disposed within and extending through the sheath. An adjustment mechanism is also operatively connected to the endoscope to longitudinally extend and retract the endoscope within the sheath.

Biopsy device

Growing community of inventors

Los Altos, CA, United States of America

James Raymond Kermode