Mayo Foundation for Medical Education and Research

Roche Molecular Systems, Inc.

Other

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

James R Uhl

Franklin R Cockerill, Iii

Thomas F Smith

Astrid Reiser

Bruce C Kline

Mark J Espy

Christian Aichinger

Arlo Wold

Randall T Hayden

Franklin R Cockerill

The present invention relates to methods of detecting the presence or absence of methicillin-resistant(MRSA) in a sample, the method comprising performing an amplifying step, a hybridizing step and a detecting step. Furthermore, the present invention relates to primers, probes and kits for the detection of MRSA.

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The invention provides methods to detect group B(GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.

The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.

Detection of group B streptococcus

The invention provides methods to detect mecA-containingspp. in biological samples using real-time PCR. Primers and probes for the detection ofare provided by the invention. Articles of manufacture containing such primers and probes for detecting mecA-containingspp. are further provided by the invention.

The invention provides methods to detect and further to detect in biological samples using real-time PCR. Primers and probes for the detection of and are provided by the invention. Articles of manufacture containing such primers and probes for detecting and are further provided by the invention.

Detection of Legionella

The invention provides methods to detect Group A Streptococcus (GAS) in biological samples using real-time PCR. Primers and probes for the detection of GAS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GAS are further provided by the invention.

Detection of group a Streptococcus

A method for selectively detecting M. tuberculosis is provided employing restriction fragment length polymorphism analysis of an enzymatic digest of the M. tuberculosis katG gene.

Mutations in the katG gene useful for detection of M. tuberculosis

A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction length polymorphism analysis to determine whether or not the DNA of said strain has an NciI-MspI restriction site at the codon corresponding to codon 463 of an M. tuberculosis katG gene consensus sequence.

Detection of isoniazid resistent strains of M. tuberculosis

A method for determining the susceptibility of a strain of M. tuberculosis to isoniazid is provided comprising employing the techniques of restriction fragment length polymorphism analysis to determine whether or not the DNA of said strain has an MspI restriction site at the codon corresponding to codons 315 or 463 of an M. tuberculosis katG gene consensus sequence.

Detection of isoniazid resistant strains of M. tuberculosis

A commode seat and lift structure include a central axle directed therethrough, with a pair of springs interposed between the commode seat and commode to effect biasing of the seat in a lifting orientation relative to the commode. The springs each include an adjuster plate and an adjuster rod threaded through the plate. The adjuster rod includes a mounting plate secured to the commode bowl to adjust the spring force.

Growing community of inventors

Rochester, MN, United States of America

James R Uhl