University of Virginia Patent Foundation

USA As Represented by Secretary of the Navy

Microvention, Inc.

Boston Scientific Medical Device Limited

James R Stone

Ivan Sepetka

George Robert Greene

Cathy Lei

Matthew R Dreher

Matthew J Bradley

Stephen T Ahlers

Kiel Douglas Neumann

Rupal Nguyen

Carl W Goforth

Carl S Goforth

Some embodiments relate to imageable radioisotopic microspheres. In some embodiments, the imageable microspheres are radiolabeled with imageable radioisotopes. In some embodiments, the imageable radioisotope is directly coupled to a surface of a substrate of the microsphere. In some embodiments, the imageable microspheres can be used as surrogate particles to predict the distribution of therapeutic microspheres comprising radiotherapeutic isotopes.

Particles functionalized with imageable radioisotopes and methods of making and use thereof

A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.

Temporary aortic occlusion device

Growing community of inventors

Charlottesville, VA, United States of America

James R Stone