Henry Ford Hospital

University of Windsor

James R Ewing

Mordechay Schlesinger

Long Jian Liu

Stephen L Brown

A scanning apparatus, is used to effect multiple images of a tumor in which a contrast agent has been localized as a detectable marker over a selected time to map the change in the imaged marker. The rate of change in the imaged marker and/or contrast intensity of the dyed tissues is used to assess tumor aggressiveness and as an early predictor of response to cancer therapy. In particular, following the marking of tumor or cancerous tissues by the initial localization of an imageable contrast agent, the rate of change in the volume and/or area of the imaged marker is used to provide an indication of tumor interstitial fluid pressure (TIFP).

Method and apparatus for diagnosis of tumor activity using tumor interstitial fluid pressure

A nuclear magnetic resonance imaging system comprising a high field solenoidal magnet providing a uniform static magnetic field surrounding a subject, an RF coil surrounding the subject, a receiver coil surrounding the subject, and a cylindrical shell of magnetic material surrounding the magnet and the RF and receiver coils. The shell is positioned such that the wall thereof lies in the area of the field of the magnet where the shell's permeability is substantially at a maximum for the imposed field such that the shell functions to substantially confine the field of the magnet to an area about the shell and the environment is not adversely affected and no additional protection is required surrounding the system.

Growing community of inventors

Detroit, MI, United States of America

James R Ewing