Harvest Technologies Corporation

Sims Level 1 Inc.

James R Ellsworth

Steven F Levesque

Paul McGovern

Wesley H Verkaart

Mark L Kibbe

Russell Hart

Ian M Kay

P Kevin Benoit

Christina J Sundstrom

A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.

Blood components separator disk

A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed.

Method and apparatus for separating fluid components

A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

Floating disk for separating blood components

A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated compoments, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

A container () receives anhydrous material to be hydrated and hydrating fluids. The hydrating fluids are introduced into the container through a fluid port () by one or more containers having hydrating fluid. The hydrating fluids may be a mixture of fluids provided in any desired proportion. The hydrated material is then ejected from the container.

Hydrating anhydrous graft materials

Floating disk for separating blood component

A centrifuge has a rotor for receiving a disposable processing unit. The centrifuge is configured such that the motor is attached to an enclosure and the enclosure is supported on a base. The connection between the base and the enclosure is a vibration isolator, and the isolator is positioned such that its effective line of action aligns with the effective plane of rotation of the rotor. In accordance with another feature of the invention, the processing units are held in a decanting position by a decant ring that moves vertically but does not rotate. The ring engages the top of the processing unit during decant and the abrasion is minimal.

Decanting centrifuge with sliding engagement between decant ring and processing unit

Decanting centrifuge with vibration isolation

A container designed for use as a disposable processing unit in a centrifuge includes first and second chambers connected by a bridge that allows transfer of fluid between the chambers. One of the chambers has a sloped floor that directs fluids to a smaller bottom portion for providing greater depth in the collected fluids. The container also includes cam surfaces that facilitate insertion of the container in a centrifuge in the desired orientation. As well, a key may be provided to ensure that the container is used in the correct centrifuge.

Sterile disposable unit

A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained are expressed.

Growing community of inventors

Marshfield, MA, United States of America

James R Ellsworth