Other

Xdx, Inc.

Quest Diagnostics Investments, Inc.

Expression Diagnostics, Inc.

Caredx, Inc.

James Prentice

Kirk E Fry

Robert Woodward

Jay Wohlgemuth

Ngoc Ly

Steven Rosenberg

MacDonald Morris

Heather R Sanders

Frederic Waldman

Kevin Z Qu

Kirk Fry

Macdonald Morris

Heather Sanders

Kevin Qu

The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.

Methods for screening solid tumors for mutations

A solar panel cap and light cap secured to a wall or parapet through the use of a fixed coping and a secured bracket. The secured bracket has a securing plate mechanically attached to a top of the wall and upper and lower extensions extending above and below the top of the wall along its sides. The fixed coping has two vertical supports on either side of a locking channel. The vertical supports are biased or resilient to secure the coping to the secured bracket with the upper extensions providing full contact along the length of the vertical supports. The locking channel is configured to slidably receive a locking insert from a solar panel cap or light cap, each configured to connect to an adjacent cap such that they are electrically coupled.

Adjustable solar panel system

A solar panel cap and light cap secured to a wall or parapet through the use of a fixed coping having two vertical supports on either side of a locking channel. The vertical supports are biased or resilient to secure the coping to the top of the parapet or wall. The locking channel is configured to slidably receive a locking insert from a solar panel cap or light cap, each configured to connect to an adjacent cap such that they are electrically coupled. The solar panel caps include a horizontal base and an angled solar panel pivotally attached on one edge to the horizontal base. Support plates are pivotally attached to opposite edges of both the horizontal base and the angled solar panel such that when they overlap and are secured to one another the angled solar panel is adjustably positionable relative to the horizontal base.

Adjustable solar panel cap and method of manufacturing same

A solar panel cap and light cap can be secured to a wall or parapet through the use of a common bracket. The bracket includes two vertical extensions on either side of a locking channel. The locking channel is configured to permanently receive a matching end, such that the matching end cannot come out of the locking channel once installed. Both the solar panel cap and light cap include the matching end. The solar panel caps and light caps are configured to connect to an adjacent cap such that they are electrically coupled. Either the solar panel caps or light caps can include a rechargeable battery such that energy stored during daylight hours can be used during the night.

Adjustable solar panel cap

Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Methods and compositions for diagnosing and monitoring transplant rejection

Growing community of inventors

San Francisco, CA, United States of America

James Prentice