Quidel Cardiovascular Inc.

Solar Turbines Inc.

James Powell

Scott Rongey

Jonathan Gary

Scott L Stafford

Luvern John Weber

Terry Toshio Akiyama

The present invention relates to compositions and methods use in designing immunoassay controls. In various aspects, the invention provides synthetic peptides comprising the sequence CPRRPYIL (SEQ ID NO: 1) or an analog thereof; ELAGLGFAELQC (SEQ ID NO: 4) or an analog thereof; and CDWRKNIDAL (SEQ ID NO: 8) or an analog thereof; specific binding reagents that bind to a CPRRPYIL (SEQ ID NO: 1), ELAGLGFAELQC (SEQ ID NO: 4) or CDWRKNIDAL (SEQ ID NO: 8) peptide; methods of producing such reagents; and assays utilizing such reagents to provide assay controls signals that are unrelated to the measurement of the analyte or analytes of interest in that no reagents used in the analyte assay(s) contribute to the control signal.

Immunoassay controls and the use thereof

The present invention relates to compositions and methods use in designing immunoassay controls. In various aspects, the invention provides synthetic peptides comprising the sequence CPRRPYIL or an analog thereof; ELAGLGFAELQC or an analog thereof; and CDWRKNIDAL or an analog thereof; specific binding reagents that bind to a CPRRPYIL, ELAGLGFAELQC or CDWRKNIDAL peptide; methods of producing such reagents; and assays utilizing such reagents to provide assay controls signals that are unrelated to the measurement of the analyte or analytes of interest in that no reagents used in the analyte assay(s) contribute to the control signal.

A gage tool () for inspecting tolerances of a gas turbine engine seal plate () includes a base plate () and a top plate (). The base plate () includes a base opening () and a slot () with an annular shape sized to receive a seal plate (). The top plate () includes a top opening (). The base opening () and top opening () each provide access to a portion of a seal plate () within the gage tool (). The gage tool () also includes a first gage () with a probe tip for measuring a variation in an outer interlacing surface () of a seal plate () and a seal slide gage () for measuring a force required to rotate the seal plate () within the gage tool.

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San Diego, CA, United States of America

James Powell