Orthovita, Inc.

Vita Special Purpose Corporation

Innovital, LLC

James Philip Murphy

Charanpreet S Bagga

Erik M Erbe

Gregory J Pomrink

James M Freid

Marissa M Conrad

Theodore D Clineff

Matthew B Havener

Jeffrey G Marx

Marissa M Darmoc

Robert J Chiasera, Jr

Zachary S Szczerbinski

Michael W Paris

Gregory Hiemenz

Maarten Persenaire

Dean A Entrekin

Harvinder Sandhu

A low-cost and simple-to-use system and method to facilitate a prophylactic pleural lavage protocol at the time of thoracostomy tube placement for traumatic hemothorax in order to reduce the need for secondary intervention for the management of retained hemothorax. The invention may be used in conjunction with existing chest tubes and be administered at the time of initial chest tube placement, and continued at the bedside (by a bedside nurse) over the duration of chest drainage, as necessary. The system includes an operator device that semi-automatically administers a pleural lavage protocol consisting of saline instillation, and suction to slow the clotting process, prevent 'gelling' of blood, and maintain drainability.

System for improving fluid drainage

The present invention generally relates to bioactive composites of polymer and glass and, more particularly, to bioactive implants. The present invention also relates to methods of manufacturing bioactive composites. The bioactive composite finds utility in a variety of load-bearing clinical applications including spine, orthopaedic and dental procedures.

Bioactive composites of polymer and glass and method for making same

Methods of preparing bioactive composites are described. Also described are methods of molding such composites. Shaped bodies comprising bioactive composites are further described.

Bioactive load-bearing composites

The present invention relates to a method of preparing a bioactive composite, the method comprising the steps of a) adding in a solid state a biocompatible polymer and a bioactive glass to an extruder to form an extrudable material; b) applying energy to the extrudable material to at least the melting temperature of the biocompatible polymer to melt mix the biocompatible polymer and bioactive glass; and c) extruding a bioactive composite.

A bioactive spinal implant used in cervical fusion, Anterior Lumbar Interbody Fusion (ALIF), Posterior Lumbar Interbody Fusion (PLIF), and Transforaminal Interbody Fusion (TLIF), having properties and geometries that enhance bone contact, stability, and fusion between adjacent vertebral bodies.

Bioactive spinal implants and method of manufacture thereof

A syringe configured to deliver viscous compositions is described, in which the syringe may include an elongate chamber having side port(s) extending therefrom. Various viscous compositions may be inserted through the side port(s) and into the elongate chamber, which may further house a plunger for ejecting the composition. One portion of the plunger may interact with a restricted opening on the chamber to inhibit removal of the plunger from the chamber; and another portion of the plunger may have a locking structure, which cooperates with a locking structure on the chamber to selectively fix the plunger with respect to the chamber. The plunger may also be fully slidable within the chamber when the locking structures of the plunger and the elongate chamber are not engaged. Related methods of using the aforementioned syringe, as well as kits including further instruments that interact with the syringe, are also disclosed.

Syringe for the delivery of viscous compositions

An apparatus for the delivery of a biological composite and a method, kit, and system for preparing a biological composite is described herein. The biological composite includes both inorganic and biological materials.

Delivery device for biological composites and method of preparation thereof

Surgical devices permitting a surgeon to access repeatedly tissue at a particular surgical site in a patient to perform multiple surgeries over time. The devices have two substantially planar and parallel leaves that are sterile, nonresorbable, and biocompatible. Each leaf forms a continuous structure and defines the entire longitudinal length of the device to accommodate the size and location of the surgical site. A base member is located in situ and adjacent the surgical site. An anchoring surface secures the device to the tissue of the patient at the surgical site. The leaves have a conjoined portion such that a manual force is required to separate the leaves, thereby expeditiously creating a pathway through which access to the tissue at the surgical site is realized with minimal tissue dissection, and the proximal ends of the leaves are not conjoined to facilitate separation of the leaves and creation of the pathway.

Growing community of inventors

Newtown Square, PA, United States of America

James Philip Murphy