Heska Corporation

James P Porter

Glenn R Frank

Keith E Rushlow

Donald L Wassom

Eric R Weber

Nancy Wisnewski

Robert B Grieve

Roy R Mondesire

The present invention includes a method to detect IgE using a human Fc epsilon receptor (FcR) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.

Method to detect IgE

The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.

The present invention includes a method to detect infection in a host animal using a Di33 protein to detect anti- Di33 antibodies in a bodily fluid of the animal. Also included is a method to detect infection in a host animal using a anti-Di33 protein to detect Di33 proteins in a bodily fluid of the animal. The present invention also relates to detection kits that include either a Di33 protein or an anti-Di33 antibody; such kits also include a composition to detect an immunocomplex between the anti-Di33 antibody and Di33 protein. The present invention also includes Di33 proteins, nucleic acid molecules encoding such proteins, as well as recombinant molecules and recombinant cells comprising such nucleic acid molecules, and anti-Di33 antibodies. Also included are methods to produce such proteins, nucleic acid molecules and antibodies.

Method to detect Dirofilaria immitis infection

The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc,R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.

The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, compositions comprising such nucleic acid molecules, and methods to use such nucleic acid molecules to produce feline Fc epsilon receptor alpha chain proteins.

Feline Fc epsilon receptor alpha chain nucleic acid molecules

The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.

Feline Fc epsilon receptor alpha chain nucleic acid molecules, and uses

Feline Fc epsilon receptor alpha chain proteins and therapeutic uses

The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc.sub..epsilon. R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.

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Fort Collins, CO, United States of America

James P Porter