Biological Dynamics, Inc.

Baxter International Inc.

Baxter Healthcare Sa

Biolinq Incorporated

Welch Allyn, Inc.

Solase Corporation

James McCanna

David Y Liu

Paul David Swanson

Eugene Tu

Robert Paul Turner

Rajaram Krishnan

Kai Yang

David Jean Charlot

Irina V Dobrovolskaya

Lucas Kumosa

Marshal Singh Dhillon

Matthew J Banet

Erik Tang

Mark Dhillon

Joshua Ray Windmiller

Juan Pablo Hinestrosa Salazar

Juscilene Menezes

Jared Rylan Tangney

David Edward Quinn

Ervin Goldfain

Lauren Nicole Miller Hayward

Alan Steven Campbell

Sirilak Sattayasamitsathit

Ashkan Arianpour

Semeon Y Litvin

Irina Dobrovolskaya

David Liu

Described herein are variations of an analyte monitoring system, including an analyte monitoring device. For example, an analyte monitoring device may include an implantable microneedle array for use in measuring one or more analytes (e.g., glucose), such as in a continuous manner. The microneedle array may include, for example, at least one microneedle including a tapered distal portion having an insulated distal apex, and an electrode on a surface of the tapered distal portion located proximal to the insulated distal apex. At least some of the microneedles may be electrically isolated such that one or more electrodes is individually addressable.

Continuous analyte monitoring system with microneedle array

A method for circumscribing an insulating barrier region around a singular conductive microneedle structure or plurality of conductive microneedle structures adhered to a fixed substrate for the purpose of spatially defining a conduit for the routing of an electrical signal from the surface of said microneedle or microneedles to the posterior surface of the substrate is disclosed herein. A microneedle-based electrochemical biosensors structure comprises a substrate, a microneedle biosensor, a primary electrically conductive element, a secondary electrically conductive element and an electrically insulative annular barrier.

Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure

The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Patch-based physiological sensor

The invention provides a neck-worn sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The neck-worn sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Physiological sensor resembling a neck-worn collar

The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.

Nucleic acid sample preparation

A miniaturized sub-nanoampere sensitivity low-noise potentiostat system is disclosed herein. The system includes an adjustable bias analog front end/potentiostat, a plurality of high input impedance and high gain difference amplifiers, means for signal filtering, a high-resolution analog-to-digital converter, and a sampling algorithm.

Miniaturized sub-nanoampere sensitivity low-noise potentiostat system

Growing community of inventors

San Diego, CA, United States of America

James McCanna