Sunnybrook Health Sciences Centre

Sunnybrook Research Institute

Nova R&d, Inc.

James Mainprize

Glenn Edwards

Oleh Antonyshyn

Martin Yaffe

Gordon Mawdsley

Tumay O Tumer

James F Asbrock

Dale G Maeding

Shi Yin

Olivier Alonzo-Proulx

Methods and apparatus are provided for forming a patient-specific surgical implant based on mold system. The apparatus comprises a forming tool and a mold that may be generated using imaging and processing techniques and rapid prototyping methods. The mold apparatus includes at least two non-adjacent surface features for securing an implant forming material (such as a titanium mesh) during the forming process, enabling the implant forming material to be stretched beyond its elastic and thus permanently deformed with the correct patient-specific curvature. The implant may include one or more anatomic surface features for guidance and registration when transferring the implant to a patient.

Method of forming patient-specific implant

Surgical mesh implant

Systems and methods for generating imaging biomarkers that indicate detectability or conspicuity of lesions that may be present in mammographic images are provided. In general, a task-based measure of a signal-to-noise ratio ('SNR') measurement of a detection task is computed over a number of small regions-of-interest ('ROIs') in an image, and the computed parameter is used to predict what detection rates should be if a lesion was present in the image. As such, the computed parameter can be used to define an imaging biomarker that is a &#x201c;masking measure&#x201d; that indicates the degree of conspicuity of lesions that may be present in a given a mammographic image.

Systems and methods for generating an imaging biomarker that indicates detectability of conspicuity of lesions in a mammographic image

An integrated application specific integrated circuit having a detection layer, a time delayed integration capability, data acquisition electronics, and a readout function is provided for detecting breast cancer in women. The detection layer receives x-ray radiation and converts the received energy to electron pairs, one of which is received by pixels. The time delay integration is on the chip and a part of the readout architecture. The detector may be a hybrid silicon detector (SiPD), a CdZnTe detector, or a GaAs detector.

High resoultion digital imaging apparatus

Growing community of inventors

Toronto, Canada

James Mainprize