Schering Corporation

James M Spitler

Neng-Yang Shih

Bandarpalle B Shankar

Joseph A Kozlowski

Ronald L Wolin

Ling Tong

Brian J Lavey

Razia Rizvi

Michael K Wong

Ashit K Ganguly

John J Piwinski

Robert G Aslanian

Kevin D McCormick

Pauline C Ting

Pietro Mangiaracina

Gregory A Reichard

Nicholas I Carruthers

Michael P Kirkup

Cheryl A Alaimo

Andrew Lupo, Jr

There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.

Cannabinoid receptor ligands

The invention relates to compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.

Compound represented by the structural formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or3;

Substituted oximes, hydrazones and olefins as neurokinin antagonists

Compound represented by the structural formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or 3;

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Westfield, NJ, United States of America

James M Spitler