Dow Agrosciences LLC

Dowelanco

Corteva Agriscience LLC

James M Renga

Yuanming Zhu

Gregory T Whiteker

Benjamin M Nugent

Kim Eric Arndt

Michael R Loso

Richard Brewer Rogers

Jim Xinpei Huang

Gary A Roth

Christian Thomas Lowe

Vidyadhar Babu Hegde

Natalie Christine Giampietro

David E Podhorez

Chenglin Yao

Kevin Gerald Meyer

Ronald Ross, Jr

John F Daeuble, Sr

Noormohamed Mohamed Niyaz

Thomas L Siddall

W John Owen

Timothy P Martin

Peter Lee Johnson

Nakyen Choy

Timothy A Boebel

Yang Cheng

Paul R Schmitzer

William C Lo

Joseck M Muhuhi

Zoltan Laszlo Benko

Lindsey Gayle Fischer

Jeremy Wilmot

Carla Nanette Yerkes

Gary D Crouse

Thomas Clarence Sparks

Joseph D Eckelbarger

Jeffrey Brian Epp

Gerald Bryan Watson

Erich W Baum

Joseph J DeMark

Ronald J Heemstra

David Hamilton Young

David Anthony Demeter

Joshua Roth

Richard B Rogers

David Laitar

William Hunter Dent, Iii

Maurice C Yap

Scott P West

Fangzheng Li

Joseph J Demark

Karla Bravo-Altamirano

Jessica Herrick

Nicholas Martin Irvine

Christopher Galliford

Francis Eugene Tisdell

Nneka Tuere Breaux

Maurice C H Yap

Nick X Wang

Katherine Anne Guenthenspberger

Jeremy Kister

Paul Richard Graupner

Kenneth E Stockman

Ronald Ross

Robert D J Froese

Brent Jeffrey Rieder

Gary David Gustafson

CaSandra Lee McLeod

Douglas Bland

Jossian Oppenheimer

Irene Mae Morrison

Matthew Lee Grandbois

Yulan C Tong

Jeff Petkus

Emily Marie Rigsbee

Neil Vincent Kirby

Robert Froese

John Todd Mathieson

Alexander P Fung

Mark W Zettler

John F Daeuble

George E Davis

William Thomas Lambert

Lindsey G Horty

Michael J Ricks

Mark V M Emonds

Miriam E Goldsmith

Kevin L McLaren

James T Pechacek

Clark S Davis

Jenifer Lynn Adamski Butz

Stephen T Heller

Jeannie Rachel Phillips Cetusic

Robert D Froese

Douglas C Bland

Francis Tisdell, Jr

William Dent

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing such molecules, and processes of using such molecules and compositions against such pests. These molecules and compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula ('Formula One'). 

Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto

4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a 3,3-dialkoxyprop-1-yne and a substituted methylene amine by a series of steps.

Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates

4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and bromination-rearrangement. 4-Alkoxy-3-hydroxypicolinic acids may be conveniently prepared from 4,6-dibromo-3-hydroxypicolinonitrile in a series of chemical steps selected from bromo substitution, nitrile hydrolysis and halogen reduction.

Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids

The invention relates to compounds of macrocyclic picolinamides of Formula I suitable to control or prevent growth of fungi. 

Macrocyclic picolinamides compounds with fungicidal activity

4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, reaction with hydrazine, halogenation, hydrolysis and esterification, and transition metal assisted coupling.

Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates

4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and bromination-rearrangement.

Process for the preparation of dibromohydroxypicolinonitrile

3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinic acids having a halogen, alkyl or mono-, di-tri- and tetra-substituted aryl substituents in the 6-position, and their acid derivatives, are herbicides demonstrating a broad spectrum of weed control.

3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides

4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a C-Calkyl propiolate and a substituted methylene amine by a series of steps.

4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange and hydrolysis, esterification and transition metal assisted coupling.

Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula ('Formula One'). 

Molecules having certain pesticidal utilities, intermediates, compositions, and processes, related thereto

4,5,6-Trichloropicolinic acid is prepared by selectively dechlorinating 3,4,5,6-tetrachloropicolinic acid with zinc and a catalyst prepared from a nickel compound and a bidentate ligand in a polar solvent.

Process for the preparation of 4,5,6-trichloropicolinic acid

Provided herein are fluoropicolinoyl fluorides and processes for their preparation. In some embodiments, provided herein is a process for the preparation of 5-fluoro-6-aryl-picolinoyl fluorides from chloropicolinoyl chlorides.

Fluoropicolinoyl fluorides and processes for their preparation

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Indianapolis, IN, United States of America

James M Renga