Novo Nordisk A/s

James M Flink

Thomas Buch-Rasmussen

Philip E Hansen

Søren Aasmul

Jens Ulrich Poulsen

Claus Juul Mortensen

Claus Juul-Mortensen

S&oslash;ren Aasmul

Jens Ulrik Poulsen

Andre Larsen

Troels Kornfelt

Peter Christian Klitgaard

Dorthe Kot Engelund

Simon Bjerregaard Jensen

Niels Kristian Klausen

Jens-Ulrik Poulsen

Gabriel Jo Slashedrgensen

Silke Møller Larsen

Peter Norland Jensen

Lars Lindgaard Hansen

Hanne Nedergaard

Pharmaceutical formulations of GLP-1 compounds and methods for preparation thereof.

Stable formulation of modified GLP-1

Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.

Dry mouldable drug formulation

Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.

The present invention relates to a method and a system for producing an elongated drug formulation being suitable for being injected through the skin of a patient with-out the use of a needle or a cannula. The drug formulation is produced by compressing a drug granulate in cavity of a system comprising a roller and a surface, wherein the roller roles over the surface thereby comprising the granulate to the formulation.

Method for producing an elongated drug formation

A cassette for storing and insertion of a solid medicine peg appears as a unit having a first bore ( ) which accommodates the medicine peg ( ) and has a diameter corresponding to the diameter of this peg ( ), a second bore ( ) in coaxial extension of the first bore ( ) and having a diameter larger than the diameter of the first bore ( ), an inserter having a shaft ( ) fitting into the first bore ( ) and a guiding head ( ) in coaxial extension of the shaft ( ) fitting into the second bore. The inserter shaft ( ) has one end adjacent to the peg ( ) and the other connected to the guiding head ( ) which projects from the cassette. The head ( ) fits into the second bore with a fitting providing a diffusion tight sealing and the distal end of the unit is closed by a membrane diffusion tightly sealing this distal end.

Cassette for storing and insertion of solid medicine

Kit for storage and mixing of agents of which at least one is liquid

Growing community of inventors

Frederiksberg, Denmark

James M Flink