Fmc Technologies, Inc.

Uwm Research Foundation, Inc.

Raytheon Company

Wisys Technology Foundation, Inc.

Marquette University

Columbia University

Wisconsin Alumni Research Foundation

Centre for Addiction and Mental Health

University Of Belgrade—faculty Of Pharmacy

Medical University of Vienna

National Taiwan University

University of Wisconsin-milwaukee Research Foundation

James M Cook

Corey Massey

Wenyuan Yin

Guanguan Li

Michael Ming-Jin Poe

David A Baker

Thiago Machado

Chad Vrla

Edward Merle Johnson, Ii

Julian Keihany

Rajeev Rajan Pillai

Ojas A Namjoshi

Dongmei Han

Jianming Yu

Qi Huang

Xiaohui He

Richard D Loehr

Douglas C Stafford

Alexander E Arnold

Michael J Mahnken

Charles W Emala

Andrew Krupa

Shengming Huang

Robert S Brinkerhoff

Miroslav M Savic

Etienne Sibille

Michael Rajesh Stephen

Tep Ungchusri

Gareth Boyd

Jean-Luc Streiff

Dan Fink

Philippe Espinasse

Gabriel Tiviroli-Melchert

Brian Swagerty

Gary Bernard

Hiteshkumar D Jain

Revathi Kodali

Jie Yang

Sundari K Rallipalli

John Francis McElroy

James H Dupont

Henri Y Kim

Robert J Cavalleri

James R Soltau

Marko Mihovilovic

Bruno Freitas

William N Patterson

Christopher Adams-Hernandez

Garrett L Hall

Werner Sieghart

Lih-Chu Chiou

Zhi-jian Wang

Sunil Dutt

Johann Rongau

Justin Taylor

Pi-Chuan Fan

Zachary Curry

Andrew Cappello

Nathanial Ramsey

Sobitha Gunatilleke

Yun Teng Johnson

Clay Dixon

Xioayan Li

Daniel Knutson

Terry S Clayton

Hernan Anzola

Gloria Forkuo

Rajwana Jahan

Ranjit Singh Verma

Cody Bedwell

Rahul Edwankar

Xiaoyan Li

Laurin Wimmer

Zhi-Jian Wang

Yaswanth Kasireddy

Pablito Derayunan

Kashi Reddy Methuku

Michael L Van Linn

Lloyd E Kinsey, Jr

Hao Zhou

Pvv Srirama Sarma

George Gallos

Chunchun Zhang

Terry Clayton

Snjezana Lelas

Edward Merle Johnson

Robert Brinkerhoff

Richard Loehr

William Albright

Mike Pursley

Nathan Ogg

Matheus Meirelles

Margot Ernst

Ranjit Verma

Zdravko Varagic

David Chan Bodin Siebert

Christopher Witzigmann

A method for performing simultaneous operations at a wellsite comprising two or more adjacent wellheads, each respectively connected to a well, may include the following steps: providing a fluid supply via upstream equipment to an intermediate supply point; fluidly connecting the intermediate supply point to a single wellhead, the fluidly connecting comprising connecting a first end of a flexible pipe to the intermediate supply point and a second end of the flexible pipe to a first wellhead; performing a wellbore operation on a first well using the fluid supply from the upstream equipment supplied to the first wellhead; disconnecting the second end of the flexible pipe from the first wellhead; and connecting the second end of the flexible pipe to a second wellhead.

Well fracture systems and methods

A pipe assembly includes a flexible pipe segment and at least one end fitting. The at least one end fitting includes an end casing coupled to the flexible pipe segment and a seal housing removably coupled to the end casing. The end casing defines a seal housing-receiving bore extending longitudinally through the end casing, and the seal housing is positioned within the seal housing-receiving bore. The seal housing defines at least one seal bore extending from an axially distal surface of the seal housing, and one or more sealing elements are seated in a respective one of the at least one seal bore. The end casing is couplable to a counterpart fitting, and the seal housing and/or the one or more sealing elements are configured to define a sealing interface with the counterpart fitting.

End fittings for flexible pipe segments

A system may include a built hydraulic fracturing system with a plurality of devices connected together and a simulation of the built hydraulic fracturing system on a software application. Additionally, a fracturing plan may be provided on the software application to include pre-made instructions to perform multiple processes in a hydraulic fracturing operation such as a sequence of valve operations to direct fluid flow through a selected path. Further, the fracturing plan may be modified to create a customized fracturing plan including the pre-made instructions and at least one modified instruction. Furthermore, the customized fracturing plan may be executed to perform at least one of the processes in the built hydraulic fracturing system.

System and method for an automated and intelligent frac pad

A control unit includes a hydraulic fluid system, a lubricant system, at least one sensor cable, an electronics module in communication with the at least one sensor cable, the hydraulic fluid system, and the lubricant system. A housing of the control unit contains the hydraulic fluid system, the lubricant system, the sensor cable(s), and the electronics module.

Modular control systems with umbilical deployment

Systems, methods, and at least one seal pocket detection assembly configured to be placed within a pressure cavity of a well tubing system. The seal pocket detection assembly includes a selectively removable insert body supporting one or more seals and one or more coils that produce an electromagnetic field extending into the bore of tubing sections of the well tubing system. The seal pocket detection assembly is configured to detect a ferrous object passing through the bore.

Seal pocket detection assembly

An illustrative modular manifold system includes, among other things, two or more modular pump manifolds, a low-pressure header, and a main high-pressure manifold. Modular pump manifolds may include a low-pressure manifold for supplying fracturing fluid or water to pumps, a high-pressure manifold for supplying fracturing fluid or water to one or more wells and a bleed-off/prime-up manifold. Each modular pump manifold of the modular manifold system is configured to be fluidly isolatable from the other modular pump manifolds. Each isolated modular pump manifold is configured to be flushed with water, bled off and primed up independently of the other modular pump manifolds. After the bleed off, maintenance procedures may be performed on pumps associated with the isolated modular pump manifold. The modular pump manifolds that are not isolated may continue in active fracing stage operations while a modular pump manifold is isolated.

Modular manifold system for continuous fluid pumping into a well

A pipe deployment system includes a vehicle, a deployment tool having a body with a spool engagement slot and a hydraulic motor mounted to the body, a spool having a pin extending along a rotational axis of the spool from an end of the spool, and an engagement spline rotationally engaging the hydraulic motor with the pin. The deployment tool is removably connected to the vehicle.

Reel deployment for centralized pad system

Provided herein are alpha5-containing GABAreceptor agonists and pharmaceutical compositions and methods of treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders using them.

Treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders with alpha5-containing GABAreceptor agonists

A modular pump skid includes a base, a prime mover mounted on the base, and one or more hydraulic pump circuits removably mounted on the base and operationally coupled to the prime mover, wherein each hydraulic pump circuit has a hydraulic pump operationally coupled to the prime mover and a hydraulically driven pump fluidly coupled to the hydraulic pump. Each hydraulic pump circuit is in a closed loop independent of other hydraulic pump circuits.

Hydraulic fracturing pump system

A modular valve tree may have two or more blocks. Additionally, a first block may have a flow passage therethrougt, with an inlet and an outlet and a second block may have a flow passage therethrough with including an inlet and an outlet. Further, an insert may be provided comprising sealing elements. The insert may be partially disposed within each of the first block and the second block and the insert has a throughbore fluidly connecting the first block outlet to the second block inlet. Furthermore, the sealing elements are configured to seal external surfaces of the insert against an internal surface of the respective flow passages. A retention system may retain the blocks in position and compress and engage one or more of the sealing elements.

Modular valve tree

A high-pressure unit (HPU) skid includes one or more hydraulic pumps, a grease pump, a hydraulic reservoir, and two or more accumulators all mounted on a portable frame. The HPU skid also includes fluidic connections to connect one or more valves to an output of the grease pump and fluidic connections to connect one or more valves to an output of at least one of the two or more accumulators. The accumulators are configured to close at least one of the one or more valves using a charged pressure. The HPU skid further includes fluidic connections to connect one or more valves to at least one of the one or more hydraulic pumps. The hydraulic pumps are configured to withdraw hydraulic fluid from the hydraulic reservoir for charging the accumulators, operating the grease pump, charging the accumulators and operating the grease pump at a same time, or operating one or more valves.

Integrated high-pressure unit

A system may have a built hydraulic fracturing system with a plurality of devices connected together and in fluid communication with one or more wells. The system may also include at least one continuous pumping operations for one or more wells and a fracturing pumping plan provided on a software application. The fracturing plan may include instructions to perform at least one continuous pumping operations for the one or more wells. The instructions may include a sequence of valve operations to direct fluid flow through a selected path into the one or more wells.

System and method for an automated and intelligent frac pumping

The present invention describes substituted benzo[f]imidazo[1,5-a][1,4]diazepines of the formula (I): wherein R, R, R, R, and X are as disclosed herein. These compounds target alpha-4 and alpha-5 GABAa receptors and are useful for the treatment of airway hyperresponsiveness and inflammation in asthma.

Substituted benzo[f]imidazo[1,5-a][1,4]diazepines as GABA(a) receptor modulators

A system includes a built hydraulic fracturing system with a plurality of devices connected together and a simulation of the built hydraulic fracturing system on a software application. Additionally, a fracturing plan may be provided on the software application to include pre-made instructions to perform multiple processes in a hydraulic fracturing operation such as a sequence of valve operations to direct fluid flow through a selected path. Further, the fracturing plan may be modified to create a customized fracturing plan including the pre-made instructions and at least one modified instruction. Furthermore, the customized fracturing plan may be executed to perform at least one of the processes in the built hydraulic fracturing system.

Growing community of inventors

Milwaukee, WI, United States of America

James M Cook