Cook Medical Technologies LLC

University of Limerick

Cook Incorporated

Cook Ireland Limited

James M Carlson

Fred T Parker, Jr

James Butler

Shyam S V Kuppurathanam

Peter Tiernan

Rebecca Sue Todd

Abbasi A Gandhi

Shay Joseph Lavelle

Michael Ryan

Ronan T Young

Paul David Devereux

Syed Ansar Md Tofail

Syed A M Tofail

Donncha Haverty

Lisa O'Donoghue

Shane Carr

Tim McGloughlin

Jeffry Scott Melsheimer

Kurt John Tekulve

Richard W Ducharme

Michael W Hardert

Mark Robert Frye

Mark Allen Magnuson

Shyam Kuppurathanam

Jessica L Burke

James Elsesser

Jason C Urbanski

Christopher L Hruska

Andrew Herold

Richard J Godlewski

Aaron Weeks

Garry Warren

Alex Etwil

Tofail Ansar Md Syed

Shyam Sv Kuppurathanam

Tim Mcgloughlin

Paul Devereaux

Rebecca S Todd

Disclosed herein is a nickel-titanium alloy comprising nickel, titanium, and at least one rare earth element. The nickel-titanium alloy comprises from about 34 at. % to about 60 at. % nickel, from about 34 at. % to about 60 at. % titanium, and from about 0.1 at. % to about 15 at. % at least one rare earth element. The nickel-titanium alloy may further include one or more additional alloying elements. In addition to radiopacity, the nickel-titanium alloy preferably exhibits superelastic or shape memory behavior. Medical devices comprising the nickel-titanium alloy and a method of making them are also disclosed.

Nickel-titanium alloy including a rare earth element

Methods and apparatuses of stents with likely reduced rates of tissue perforation are provided. Some embodiments include reducing the profile of a portion of the stent using a wire profile reduction electropolishing bath and/or other wire profile reduction means.

Reduced wire profile stent

The disclosure relates to a woven fabric for use in an implantable medical device. The woven fabric comprises shape memory element strands woven with textile strands. At least one of the shape memory element strands has at least one float of at least five textile strands between binding points.

Woven fabric with shape memory element strands

A system for endoluminally delivering and deploying a prosthesis includes a prosthesis comprising a self-expanding stent and a cover for retaining at least a portion of the self-expanding stent. The stent is biased into contact with an inner surface of the cover. The inner surface has a hardness that is equal to or greater than the hardness of the stent. Additional aspects of the invention are disclosed and include a method of manufacturing an endoluminal prosthesis delivery and deployment system.

Delivery device for an endoluminal prosthesis

A mixture of powders for preparing a sintered nickel-titanium-rare earth (Ni&#x2014;Ti&#x2014;RE) alloy includes Ni&#x2014;Ti alloy powders comprising from about 55 wt. % Ni to about 61 wt. % Ni and from about 39 wt. % Ti to about 45 wt. % Ti, and RE alloy powders comprising a RE element.

Mixture of powders for preparing a sintered nickel-titanium-rare earth metal (Ni-Ti-RE) alloy

A nickel-titanium-rare earth (Ni&#x2014;Ti-RE) alloy comprises nickel at a concentration of from about 35 at. % to about 65 at. %, a rare earth element at a concentration of from about 1.5 at. % to about 15 at. %, boron at a concentration of up to about 0.1 at. %, with the balance of the alloy being titanium. In addition to enhanced radiopacity compared to binary Ni&#x2014;Ti alloys and improved workability, the Ni&#x2014;Ti-RE alloy preferably exhibits superelastic behavior. A method of processing a Ni&#x2014;Ti-RE alloy includes providing a nickel-titanium-rare earth alloy comprising nickel at a concentration of from about 35 at. % to about 65 at. %, a rare earth element at a concentration of from about 1.5 at. % to about 15 at. %, the balance being titanium; heating the alloy in a homogenization temperature range below a critical temperature; and forming spheroids of a rare earth-rich second phase in the alloy while in the homogenization temperature range.

Nickel-titanium-rare earth alloy and method of processing the alloy

A woven fabric for an implantable medical device includes a plurality of carbon nanotube strands interwoven with a plurality of textile strands, where each carbon nanotube strand comprises a plurality of carbon nanotubes. An implantable medical device comprises a component and a fabric secured to the component, where the fabric includes a plurality of woven carbon nanotube strands, and each of the carbon nanotube strands comprises a plurality of carbon nanotubes.

Woven fabric with carbon nanotube strands

The disclosure relates to a woven fabric for use in an implantable medical device. The woven fabric has shape memory element strands woven with textile strands. At least one of the shape memory element strands has at least one float of at least five textile strands between binding points.

A method of loading a medical device into a delivery system includes providing a two-stage shape memory alloy at a temperature at which at least a portion of the alloy includes austenite. A stress which is sufficient to form R-phase from at least a portion of the austenite is applied to the medical device at the temperature. A delivery configuration of the medical device is obtained, and the medical device is loaded into a restraining member. Preferably, the delivery configuration of the medical device includes stress-induced R-phase.

Method of loading a medical device into a delivery system

Medical devices are made visible under ultrasonic or magnetic imaging techniques by adding a series of features on their surfaces. The features are desirably placed at more than one angle to the surface in order to enhance the visibility of the surface. Laser-machining can make a series of depressions or voids that are symmetric with respect to the surface and another series of depressions or voids that are non-symmetric. The pattern of voids is also varied by using more than one size of void, the depth of the voids, and the distribution of voids, i.e. more voids in some areas than others.

Echogenic medical device and method of forming echogenic surface

A stent including a stent wire comprising a plurality of filaments twisted into a bundle having a helix, the stent wire bent into a pattern having a plurality of substantially straight wire sections separated by a plurality of bends. The pattern of the stent wire is spirally wound about a central axis in the same direction as the helix formed by the plurality of filaments. Each of the filaments in a bend have a cylindrical cross-section where at least one of the plurality of filaments is displaced and spaced from an immediately adjacent filament in the bend.

Multi-strand helical stent

The present invention provides a wire guide () suitable for use in a body vessel, such as a peripheral vessel. The wire guide comprises a core member () and a first coiled member (), each having proximal and distal ends. In one embodiment, the core member comprises at least one recessed portion (), wherein the proximal end of the first coiled member is seated at least partially within the recessed portion to form a substantially flush exterior surface with the core member. The wire guide further preferably comprises a second coiled member () having proximal and distal ends, wherein the second coiled member is disposed distal to the first coiled member. The distal end of the first coiled member may be partially intertwined with the proximal end of. the second coiled member. A shaping ribbon () may be disposed substantially beneath the second coiled member to achieve a desired curvature at the distal tip of the wire guide.

Wire guide

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Bloomington, IN, United States of America

James M Carlson