Nxstage Medical, Inc.

Vasca, Inc.

Cobe Laboratories, Inc.

Gambro, Inc.

B. Braun Medical Inc.

Dsu Medical Corporation

Vasco, Inc.

Nstage Medical, Inc.

James M Brugger

Jeffrey H Burbank

Dennis M Treu

William J Schnell

Mark T Wyeth

Scott W Newell

Goetz Friederichs

David Desouza

Daniel Joseph Rubery, Jr

William K Weigel

Joseph E Turk, Jr

Charles David Finch

Jerome James

Garrett Casey

Kenneth Everett Buckler

Brian Green

George W Buffaloe, Iv

John H Wang

Steven A White

Christopher S McDowell

Francis T Ogawa

Charles David Finch, Jr

C David Finch

Steven C Alford

Orlando Soto

David S Utterberg

Christopher D Pierson

Martin Stillig

Hendrik Klass Kuiper

Dan Lee Hendrickson

Keith David J Wheeler

Hendrik E Kuiper

Gerald Beathard

Gregory Yantz

Roy Sven Hovland

James Ian Johnson

Robert W Thomas

Amanda Wozniak

Robert Paul McCarty

Mark Florence

David Farias De Souza

Paul F Marad

Joseph Rausa

Helmut W Frey

Christopher S Mcdowell

Barry Neil Fulkerson

Keith J Manica

William G Palsulich

Hendrik Klaas Kuiper

Hubert S Smith, Iii

Joseph Turk

Jeffery H Burbank

R Michael Hofmann

G Keith Andrews

Eugene Cole

Steve A White

John E Moran

Hendrick K Kuiper

Jeff Burbank

Keith J Wheeler

Teresa L Oberbreckling

Adam G Mcdermott

Dritan Kurshumi

Götz Friederichs

A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.

Filtration system for preparation of fluids for medical applications

A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water.

Medicament preparation and treatment devices, methods, and systems

A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder.

A method of making a needle guard includes providing a mold having a portion defining a volume, the volume being a hollow cylinder with non-uniform walls with a pair of slots therein, the slots being open at one end and closed at the other end, the pair of slots having a major portion of constant width. The walls are thicker at the other end than at the one end. The method includes filling the volume with polymer and releasing a molded part from said mold and cooling a molded part resulting from the filling and releasing such that temperature that the widths of the pair of slots is non-uniform after cooling. The needle guard has upper and lower jaws defining a channel and coming together at a hinge. A winged needle can be inserted between the jaws, with the wings of the winged needle passing through slots between the jaws.

Needle guard

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Flow balancing devices, methods, and systems

A treatment device system includes a treatment machine for generating a custom peritoneal dialysis solution and has at least one fluid conveyor. The treatment machine has a controller with a first memory and is configured to produce the custom peritoneal dialysis solution by causing the fluid conveyor to mix purified water and at least one concentrate. A water purifier is in fluid communication with, and provides the purified water to, the treatment machine. The water purifier has an internal central controller to control preparation of the purified water, the internal central controller having a second memory. Further, the controller of the treatment machine transmits data, based on a prescription sent from a server to the treatment machine, via a wired or wireless control line to the internal central controller of the water purifier.

Peritoneal dialysis systems, devices, and methods

Features for protecting against leaks in a fluid circuit are disclosed. In an embodiment, a first indicator of a leak is used to trigger confirmation by blood flow reversal and air detection in the blood circuit. A method for performing a blood treatment includes, at blood treatment machine, pumping blood to a patient through a first blood line. Further, at a controller of the blood treatment machine, a first signal is received, indicating a probability of a leak in the first blood line. Responsively to the first signal, the controller commands a leak verification operation and receives a second signal indicating whether a leak in the first blood line is verified. Further, a leak indicating signal is generated if the second signal indicates a leak is verified.

Medical device leak sensing devices, methods, and systems

A method for measuring pressure includes securing a flow channel to a chassis of a measurement device, the flow channel having a flexible wall with a first mechanical engagement feature presented from an external surface thereof. The method also includes engaging the mechanical engagement feature with a complementary engagement member connected to a force transducer, the securing being effective to immobilize the flow channel relative to the force transducer, and detecting at least one of the position and orientation of the of the flow channel relative to transducer and comparing to at least one of a predefined position and orientation. Further, the method includes generating a signal responsive to the detecting, flowing a fluid through the flow channel, and transmitting forces caused by displacement of the flexible wall through the complementary engagement member to the force transducer. Further, electrical signals are generated responsively to a state of the force transducer.

Pressure measurement devices, methods, and systems

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

Fluid management and measurement systems, devices, and methods

Fluid couplings prevent or discourage misconnection of fluid lines. In embodiments, a coupling device includes multiple male and female connectors that are joined to a common line. The coupling device is mated to a matching coupling device only when all the multiple male and female connectors are properly joined. If any of the connectors is not properly mated to a corresponding one, the coupling will leak, since the connectors on each side are joined to a furcating channel. In embodiments, the coupling devices are made unique by providing an arrangement of the connectors, number of connectors, shape of connectors or arrangement of interfering connector parts that ensure that any attempt to improperly couple two fluid lines will result in the incomplete mating and thereby cause leakage of the fluid, failure of the coupling to engage, or otherwise cause the attempt to connect to fail.

Methods, devices, and systems for coupling fluid lines

A flow switch device includes a flow switch with four ports oriented at 90 degree intervals around a center of the flow switch. The flow switch is of a type that forms selectable flow passages between ports separated by 90 degrees and blocks flow between ports separated by 180 degrees in each of multiple selected positions. Two of the ports are connected to fixed flow passages and each of the fixed flow passages defines a flow path toward a remote port separated from each of the fixed flow passages by 180 degrees so that each of the fixed flow passages and a respective remote port are positioned in pairs on opposite sides of the flow switch.

Flow reversing device

A medical treatment device is configured to be used during a treatment session at a first location and includes a medical treatment component configured to perform at least one of hemodialysis, hemofiltration, and peritoneal dialysis on a patient during the treatment session at the first location. The device also includes a monitoring system configured to receive data from one or more sensors connected to the monitoring system, and to confirm a presence of an authorized helper at the first location. A user interface permits an operator to control functions of the medical treatment component and the monitoring system is configured to perform the presence confirmation automatically and at the predefined time intervals during the treatment session. The monitoring system is also configured to generate an alarm and to cause the medical treatment component to go into a failsafe operational mode.

Safety features for medical devices requiring assistance and supervision

According to embodiments, priming systems, methods, and devices are disclosed which allow medical treatment devices which pump fluid to be primed with minimal operator intervention and a high level of convenience. A blood circuit with a filter fitted with one or more air vents on a non-blood compartment is attached to a treatment system and priming fluid pumped slowly through the blood circuit in a loop. The source of fluid may be elevated, or the pumping may generate pressure, such that priming fluid is forced through the membrane of the filter and out the air vent(s). In embodiments, the vents are hydrophobic which prevent fluid from being ejected, so the priming system can run without intervention.

Fluid circuit priming methods, devices, and systems

Peritoneal dialysis admixing and/or treatment devices, methods, and systems are disclosed. The systems, methods, and devices provide high-level guarantees of sterility and employs relatively inexpensive disposable components to provide pumping. Disclosed systems, methods, and devices and features thereof are adapted for point of use generation of medicament. In particular admixing systems that employ independently-replaceable long term concentrate are disclosed. Features are directed to assurance of sterility and accurate admixing of water and concentrate to generate ready-to-use medicaments and other benefits.

Peritoneal dialysis fluid preparation and/or treatment devices methods and systems

Growing community of inventors

Newburyport, MA, United States of America

James M Brugger