W. R. Grace Co.-conn.

W. R. Grace Co.

Repligen Corporation

James M Bogdanor

William A Welsh

James Neil Pryor

Feng Gu

James R Rusche

James Ronald Peyser

Thomas Pauly

Dennis McCreary

Gabriella J Toeneboehn

Surya Kiran Chodavarapu

Walter M Cheek, Iii

Chromatography media and devices containing chromatography media are disclosed. Methods of making chromatography devices and methods of using chromatography devices containing the chromatography media are also disclosed.

Affinity chromatography media and chromatography devices

Impurities, which may include soaps, gums, phospholipids and pigments, can be removed from chemically or physically refined glyceride oils in a dual phase adsorption and treatment process. In the first phase, the oil is contacted with amorphous silica to remove phospholipids and soaps or gums or both. In the second phase, the oil is passed through a packed bed of a pigment removal agent for decolorizing glyceride oils.

Dual phase adsorption and treatment of glyceride oils

A modified physical adsorption process is described in which small quantities of caustic are added to glyceride oils, fatty chemicals or wax esters having an FFA level sufficient to create about 20 to 3,000 ppm soaps. The soaps, together with impurities, are removed by adsorption onto amorphous silica.

MPR process for treating glyceride oils, fatty chemicals and wax esters

Adsorbents comprising amorphous silicas with effective average pore diameters of up to about 5000 Angstroms are useful in processes for the removal of soaps and phospholipids (along with associated metal ions) from caustic treated, primary centrifuged, water-wash centrifuged or caustic refined glyceride oils.

Modified caustic refining of glyceride oils for removal of soaps and

Acid-treated amorphous silica has superior properties for the removal of phospholipids and chlorophyll from glyceride oils. The acid-treated adsorbent comprises a high surface area amorphous silica on which is supported an acid having a pK.sub.a of about 3.5 or lower.

Adsorptive material for the removal of chlorophyll, color bodies and

Phospholipids and/or chlorophyll and other color bodies are removed from glyderide oil by contacting the oil with an acid-treated amorphous silica adsorbent comprising a high surface area amorphous silica on which is supported an acid having a pK.sub.a of about 3.5 or lower.

Growing community of inventors

Columbia, MD, United States of America

James M Bogdanor