Boehringer Mannheim Gmbh

Roche Diabetes Care, Inc.

F. Hoffmann-La Roche Ag

James L Maxwell

David W Burke

Morris J Young

Rick L Collins

Martin T Gerber

Zindel Herbert Heller

Stefan Weinert

Loy M Vail

Edna C Probst

Lance S Kuhn

A method for calculating a coagulation characteristic of a sample of blood, a blood fraction, or a control comprises generating an output signal indicative of coagulation of the sample, sampling the output signal at a sampling rate for a predetermined time to provide a plurality of sampled signal values, storing the sampled signal values, rectifying the stored sampled signal values to provide a plurality of envelope values, and storing the envelope values. The stored envelope values are examined in reverse time order to determine a slope of the envelope at each of the stored envelope values. All relative maxima in the stored envelope values are identified. A range of stored envelope values corresponding to each relative maximum is determined. The identified relative maxima are compared to locate an absolute maximum in the stored envelope values. The coagulation characteristic is then calculated from the stored envelope values within the predetermined range of envelope values corresponding to the absolute maximum.

Method and apparatus for calculating a coagulation characteristic of a

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Carmel, IN, United States of America

James L Maxwell