Akzo N.v.

Akzo Nobel N.v.

Biomerieux, Inc.

James L DiGuiseppi

Thurman C Thorpe

James E Turner

Richard C Driscoll

Michael J Calandra

John D Walsh

Scott R Jeffrey

Diederik Engbersen

Lanny V Grade

Carmella S Moody

John Walsh

Diederik Engersen

Scott Jeffrey

An integrated filtration and detection device for collecting and detecting the growth of microorganisms in a specimen includes a container defining a chamber therein. The container has an inlet and an outlet in fluid communication with the chamber. A filter is mounted in the chamber between the inlet and the outlet. A sensor is mounted in the chamber. The sensor is operative to exhibit a change in a measurable property thereof upon exposure to changes in the chamber due to microbial growth.

Integrated filtration and detection device

An apparatus and method for mixing/agitating microorganism culture bottles includes a wheel in which culture bottles are placed, with the wheel being set at an angle from vertical so that bottles are not inverted during rotation. A sensor such as a florescence or colorimetric sensor for carbon dioxide is disposed along the flat bottom surface of each of the bottles. Once during each revolution the bottles pass across a photodiode/light emitting diode pair (for a calorimetric system). A sensor transmits light emitted by the LED to the photodiode. At the same instant, an infrared reflective objective sensor, emitting on a digital rotary encoder, determines the bottle number. The change in sensor transmittance is directly related to cell growth so that bottles positive for growth can be detected by suitable software.

Device for detecting microorganisms

A device and method for detecting microorganisms in a specimen by culturing the specimen in a sealable specimen container with a culture medium and detecting microorganisms in the specimen by measuring changes in pressure within the container caused by their metabolic activity during culturing. Pressure changes are measured using a sensor having a deformable section in communication with the container and a piezoelectric apparatus, such that the piezoelectric apparatus is deformed by changes in pressure within the specimen container and an electrical signal is produced by the deformation. The electrical signal is processed to detect any change in the rate of change of pressure, and thus detect the growth of microorganisms.

A device and method for detecting microorganisms in a specimen by culturing the specimen in a sealable specimen container with a culture medium and detecting microorganisms in the specimen-by measuring changes in pressure within the container caused by their metabolic activity during culturing. Pressure changes are measured using a sensor having a deformable section in communication with the container and a piezoelectric apparatus, such that the piezoelectric apparatus is deformed by changes in pressure within the specimen container and an electrical signal is produced by the deformation. The electrical signal is processed to detect any change in the rate of change of pressure, and thus detect the growth of microorganisms.

Device for detecting microorganisms using piezoelectric means

An instrument and a sealable, sterilizable vessel for detecting the presence of microorganisms in a specimen, the vessel containing a liquid culture medium and a sensor means with an indicator medium therein. Changes in the indicator medium resulting from pH change or change in CO.sub.2 concentration in the medium are detected from outside the vessel.

Method for detecting microorganisms

The present invention relates to a device and method of detecting microorganisms in a rapid manner and increasing the number of microorganisms detected during the culturing of a sample by the addition of resinous and non-resin adsorbents and molecular sieves in the growth media. These agents have been found to neutralize or remove inhibitory and antimicrobial substances found in samples and media.

Device and method for enhanced recovery and detection of microbial

Rubber stopper

An instrument and a sealable vessel for detecting the presence of microorganisms in a specimen, the vessel containing a liquid culture medium communicating with a sensor means containing an indicator medium therein. Changes in the indicator medium resulting from pH change or change in CO.sub.2 concentration in the medium are detected from outside the vessel.

Device and method for detecting microorganisms

A support attachment for use with a holding unit having at least two adjacent cavities with longitudinally axes provides sufficient pressure to squarely hold and stabilize bottles within the cavities. The support attachment has a central axis and includes a plate adapted to be fitted to the holding unit and a pair of elongated legs in symmetrically spaced relationship with respect to the central axis for supporting bottles held in two adjacent cavities in the holding unit. Each leg extends, in the same direction, from opposite ends of the plate and has first and second ends. The first ends are joined at substantially right angles to the plate and the second ends are normally biased toward one another so that when the plate is fitted onto the holding unit, one of the legs extends longitudinally into one of the adjacent cavities while the other leg extends into another adjacent cavity.

Growing community of inventors

Durham, NC, United States of America

James L DiGuiseppi