Biosense Webster, Inc.

Benvenue Medical, Inc.

Spinal Elements, Inc.

Other

Uber Technologies, Inc.

Biosence Webster, Inc.

James K Lee

Laurent B Schaller

Jeffrey L Emery

Timothy J McGrath

Martin F O'Sullivan

Ryan Jeffrey Connolly

Steven Golden

David Needleman

John E Ashley

J Brook Burley

Benjamin D McDaniel

Irma P Hill

Douglas M Lorang

Andrew Huffmaster

Ebrahim Mohammad Quddus

Sandeep Kunwar

Russell Borg

Ricardo J Simmons

Jeffrey A Doelling

Mark Y Hirotsuka

Richard G Fessler

Larry T Khoo

Frederick J Serrahsu

Helson Pacheco-Serrant

Patricia McHale

Mario A Solis

Robert Alan Mest

Michael Olen Zirkle

Chad Allen Lieber

Bart-Jan Korteling

Pierre Jais

Richard Bautista

Harold Eicher

Lisa Guo

Gerhard Hindricks

Hans Kottkamp

Qing Feng

Robert F Ocariz

Songyan Hou

Jun Jiang

Ximing Chen

Daniel Bilen

Atul Kakkur

Sergey Gitlin

Timothy J Mcgrath

David S Needleman

Brook J Burley

Irma Hill

Methods and apparatus are disclosed for distracting tissue. The devices and methods may include insertion of first and second elongated members into the space between two tissue layers, with an augmenting elongated member at least partially inserted therebetween to form a distraction device between the tissues to be distracted. At least one of the first and second elongated members may be formed of a flexible core member with a plurality of rigid veneer members spaced along the length of the core member. At least one of the elongated members may include a shaping member that automatically moves from a generally linear configuration to a generally less linear configuration. A deployment catheter may include a deformable distal end to allow augmentation of the tissue distraction device during implantation. An injection aid may be provided for introducing a filler material into an interior defined by a deployed tissue distraction device.

Minimally invasive interbody fusion

An apparatus for disrupting tissue in the intervertebral disc space that includes a barrier member having a first configuration for insertion into the disc space and a second configuration when deployed within the disc space. The second configuration of the barrier member is adapted to at least partially define a perimeter of a working region within the disc space. The apparatus also includes a tissue disruption tool configured for insertion into the working region.

Apparatus and methods for disrupting inter vertebral disc tissue

A network system for managing a network-based service (e.g., an on-demand transport service) is configured to pre-compute, based on historical data, a plurality of service metrics that are maintained in a searchable database. In response to user interaction with a user application to view available service options, the user application can cause session data indicating start and service locations to be transmitted to the network system. In response, the network system can translate the start and service locations to a first and second search keys, respectively. The search keys can be used to query the database for the relevant service metric for the session. The network system can transmit the relevant service metric to the user device to enable the user device to display information relating to the session (e.g., a price for requesting the network-based service) that is based at least in part on the relevant service metric.

Pre-computed service metric lookup for a network-based service

Apparatus and methods for disrupting intervertebral disc tissue

A catheter enables real-time light measurements, for example, without limitation, diffuse reflectance, fluorescence, etc., from biological materials, such as tissue (including blood), while performing RF ablation. The catheter tip design isolates illumination and collection paths within the tip electrode such that light for illuminating the tissue of interest (e.g., cardiac tissue or blood) is isolated within the tip electrode from light that returns from the tissue to the catheter tip, and vice versa. Such a design advantageously avoids saturation of the optical detector, and ensures diffusion of the illumination light within the medium of interest. The catheter has a catheter body and a tip electrode with a shell wall and a hollow cavity. The shell wall has at least an illumination opening and a collection opening. The catheter further includes a first fiber optic cable in communication with the illumination opening, and a second fiber optic cable in communication with the hollow cavity, wherein light emitted from the first fiber optic cable exits the tip electrode to reach tissue through the illumination opening in defining a first path and returns to the tip electrode from the tissue into the hollow cavity through the collection opening in defining a second path, the first and second paths being optically isolated from each other within the tip electrode. The invention also includes a method of making an ablation electrode tip defining isolated optical paths with in the tip electrode for light exiting the tip electrode and light returning to the tip electrode.

Catheter with omni-directional optical tip having isolated optical paths

A deflectable device, such as a catheter, is provided that includes a hinge that enhances the ability of the device to deflect or bend within a predetermined plane. The catheter comprises an elongated tubular catheter body having proximal and distal ends and at least one lumen extending therethrough. A distal segment is provided distal to the distal end of the catheter body. A tubular hinge is provided between the distal end of the catheter body and the proximal end of the distal segment. The hinge has an axis and at least one lumen extending therethrough. The tube includes at least one slot, and preferably a plurality of slots, extending part of the way through the hinge generally transverse to the axis of the hinge.

Deflectable catheter with hinge

A catheter for ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body having proximal and distal ends. An electrode assembly is provided at the distal end of the catheter body. The electrode assembly including a porous electrode arrangement that is generally transverse to the catheter body. The porous electrode arrangement comprises one or more electrodes electrically connected to a suitable energy source and a porous sleeve mounted in surrounding relation to the one or more electrodes and defining an open space between the porous sleeve and the one more electrodes. One or more irrigation openings fluidly connect the open space to a lumen extending through the catheter through which fluid can pass. In use, fluid passes through the lumen in the catheter, through the one or more irrigation openings, into the open space and through the porous sleeve.

Enhanced ablation and mapping catheter and method for treating atrial fibrillation

Method and apparatus are disclosed for distracting tissue and particularly spinal tissue. The device and method may include insertion of at least one elongated member and an augmenting member to form a structure between the tissues to be distraction, such that a dimensional aspect of the structure is augmented upon movement of the augmenting structure.

Devices for treating the spine

Methods and apparatus are disclosed for distracting tissue. The devices and methods may include insertion of first and second elongated members into the space between two tissue layers, with an augmenting elongated member inserted therebetween to form a distraction device between the tissues to be distracted. The distraction device defines a generally annular configuration, with a locking member secured to one of the elongated members at a plurality of locations to maintain the distraction device in the generally annular configuration. The augmenting elongated member may be shorter than the first and second elongated members such that a window is defined between the proximal and distal ends of the augmenting elongated member when the distraction device and the first and second elongated members are in the generally annular configuration. Bone graft material or bone filler may be introduced into the interior of the distraction device through the window.

Spinal fusion implants and devices and methods for deploying such implants

Growing community of inventors

Pasadena, CA, United States of America

James K Lee