Gen-probe, Inc.

Rasirc, Inc.

Ml Technology Venture

Gen-probe Products Company

Gen-probe Incorported

James John Hogan

Shannon Kaplan

Sherrol Hoffa McDonough

Jennifer Jill Bungo

Jo Ann Kop

Richard Dana Smith

Michael R Reshatoff

Kristin W Livezey

Patricia C Gordon

Irene Andruszkiewicz

Michael McClellan Becker

Jeffrey J Spiegelman

Daniel Alvarez, Jr

Reinhold B Pollner

Edgar Ong

Philip W Hammond

Russell J Holmes

Richard J Smith

Marie K Hudspeth

Norman C Nelson

Lyle J Arnold

William G Weisburg

Sylvia Ann Norman

Curt L Milliman

Elizabeth M Marlowe

Robert Bezverkov

Joann Kop

JoAnn Kop

Nick Mark Carter

Yeasing Y Yang

Diane L McAllister

Gary G Bee

Christopher Ramos

Edward Heinlein

Zohreh Shamsi

Alex Deptala

Elizabeth M Goslow

Vivian Jonas

Shannon K Kaplan

The disclosed invention is related to compositions, kits and methods comprising one or more oligomers targeting 16S rRNA target nucleic acid fromspeciesand/or. Compositions include amplification oligomers, detection probe oligomers and/or target capture oligomers. Kits and methods comprise at least one of these oligomers.

Compositions, kits and methods for detection of campylobacter nucleic acid

Provided are compositions, kits, and methods for the identification of. In certain aspects and embodiments, the compositions, kits, and methods may provide improvements in relation to specificity, sensitivity, and speed of detection.

Compositions, kits and related methods for the detection and/or monitoring of

Provided are compositions, kits, and methods for the identification ofIn certain aspects and embodiments, the compositions, kits, and methods may provide improvements in relation to specificity, sensitivity, and speed of detection.

Compositions, kits and related methods for the detection and/or monitoring of salmonella

Compositions, reaction mixtures, kits and methods used in amplifying and detecting nucleic acids from various species of the class Mollicutes. Particular regions of the 23S rRNA or its gene have been identified as preferred targets for nucleic acid amplification reactions of a sample suspected containing at least one species of Mollicutes. Some oligomers comprise tag regions, target closing regions, promoter sequences, and/or binding moieties. Samples can be from any source suspected of containing a species of the class Mollicutes. Preferred sample sources include bioreactors, cell lines, cell culture wares and pharmaceutical manufacturing wares.

Compositions and methods for detecting nucleic acid from Mollicutes

Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for16S or 23S rRNA sequences or DNA encoding 16S or 23S rRNA. Methods are disclosed for detecting the presence ofin samples by using the disclosed compositions in methods that include in vitro nucleic acid amplification of a 16S rRNA sequence or DNA encoding the 16S rRNA sequence, or of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product.

Compositions and methods to detectnucleic acid

The present invention provides compositions, methods and kits for the species-specific detection of

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Methods and delivery systems for providing a gas phase of a multi-component liquid source for delivery to a critical process application are provided. The methods include concentration of a component of the liquid source which is less volatile than water for delivery of a gas stream comprising the less volatile component to a critical process application. Critical process applications include decontamination and microelectronic processing applications.

Methods and systems for delivering process gases to critical process applications

Methods, systems, and devices for decontaminating materials containing biological or biologically derived materials, such as microorganisms or DNA products, are provided. The methods, systems, and devices may be used for decontaminating or sterilizing materials, such as surfaces, including, but not limited to reducing the number of viable microorganisms on surfaces. The methods, systems, and devices may further be used for rendering DNA non-amplifiable in nucleic acid amplification reactions that synthesize DNA amplification products.

Method and system for decontaminating materials

Compositions and methods for detecting nucleic acid from mollicutes

Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, and detection probes that hybridize specifically to23S rRNA sequences or DNA encoding 23S rRNA. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of23S rRNA sequences or DNA encoding 23S rRNA. Methods are disclosed for amplifying and/or detecting the presence ofin samples by using the disclosed compositions in in vitro methods that include nucleic acid amplification and/or detection of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of23S rRNA sequences or DNA encoding 23S rRNA.

Compositions and methods to detect Legionella pneumophila nucleic acid

Compositions, kits and related methods for the detection and/or monitoring of listeria

Growing community of inventors

Coronado, CA, United States of America

James John Hogan